[1]石剑 魏建南 李萍① 汪俊① 王媛 杨勇 王敏 郑爱秋**.超声引导真空辅助旋切与局部扩大切除治疗乳腺良性叶状肿瘤的疗效比较[J].中国微创外科杂志,2021,01(7):615-618.
　Shi Jian*,Wei Jiannan*,Li Ping,et al.Efficacy Comparison of Ultrasoundguided Vacuumassisted Excisional Biopsy and Wide Local Excision for Benign Breast Phyllodes Tumor[J].Chinese Journal of Minimally Invasive Surgery,2021,01(7):615-618.
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超声引导真空辅助旋切与局部扩大切除治疗乳腺良性叶状肿瘤的疗效比较()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
01
期数:
2021年7期
页码:
615-618
栏目:
临床研究
出版日期:
2021-07-25

文章信息/Info

Title:
Efficacy Comparison of Ultrasoundguided Vacuumassisted Excisional Biopsy and Wide Local Excision for Benign Breast Phyllodes Tumor
作者:
石剑 魏建南 李萍① 汪俊① 王媛 杨勇 王敏 郑爱秋**
（香港大学深圳医院乳腺外科，深圳518048）
Author(s):
Shi Jian*;  Wei Jiannan*;  Li Ping;  et al.
*Devision of Breast Surgery, University of Hong Kong-Shenzhen Hospital, Shenzhen 518048, China
关键词:
乳腺; 叶状肿瘤; 真空辅助旋切术
Keywords:
Breast; Phyllodes tumor; Vacuumassisted excisional biopsy
文献标志码:
A
摘要:
目的比较超声引导真空辅助旋切术（vacuumassisted excisional biopsy，VAB）与传统局部扩大切除术（wide local excision，WLE）治疗3 cm以下乳腺良性叶状肿瘤（phyllodes tumor，PT）的疗效。方法回顾性分析2014年7月~2020年3月94例乳腺良性叶状肿瘤资料，其中VAB组22例，WLE组72例。结果94例均顺利完成手术，共切除叶状肿瘤103枚，超声均确认病灶完全切除，无术中并发症。排除9例伴不典型增生及3例伴原位癌，VAB组19例中位随访47个月（14~80个月），局部复发率15.8%（3/19）；WLE组63例中位随访33个月（12~80个月），局部复发率11.1%（7/63）。2组局部复发率差异无统计学意义（logrank χ2=0.214，P=0.644）。WLE组切缘阴性者局部复发率为9.4%（3/32），切缘阳性者为129%（4/31），差异无统计学意义（χ2=0.002，P=0.964）。结论超声引导VAB治疗乳腺良性叶状肿瘤安全有效。
Abstract:
ObjectiveTo compare the efficacy of vacuumassisted excisional biopsy (VAB) and traditional wide local excision (WLE) in the treatment of benign phyllodes tumor (PT) of the breast less than 3 cm.MethodsThe data of 94 cases of benign phyllodes breast tumors from July 2014 to March 2020 were retrospectively analyzed, including 22 cases in the VAB group and 72 cases in the WLE group.ResultsAll the 94 cases were successfully operated. A total of 103 phyllodes tumors were resected. Ultrasonography confirmed complete resection of lesions without intraoperative complications. Nine patients with atypical hyperplasia and 3 patients with carcinoma in situ were excluded. In the VAB group, the median followup time of 19 patients was 47 months (range, 14-80 months) and the local recurrence rate was 15.8% (3/19). In the WLE group, the median followup time of 63 patients was 33 months (range, 12-80 months) and the local recurrence rate was 11.1% (7/63). There was no significant difference in the local recurrence rate between the two groups (logrank χ2=0.214, P=0.644). In the WLE group, the local recurrence rate was 9.4% (3/32) in patients with negative margin and 12.9% (4/31) in patients with positive margin, with the difference not statistically significant (χ2=0.002, P=0.964).ConclusionUltrasoundguided vacuumassisted excisional biopsy is safe and effective in the treatment of benign PT of breast.

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备注/Memo

备注/Memo:
基金项目：广东省医学科学技术研究基金（A2018194）**通讯作者，Email：zhengaq@hkuszh.org ①病理科
更新日期/Last Update: 2021-10-11