[1]袁博,王武亮**,邓克红,等.诺舒治疗异常子宫出血38例[J].中国微创外科杂志,2017,17(5):418-421.
　Yuan Bo,Wang Wuliang,Deng Kehong,et al.NovaSure for Abnormal Uterine Bleeding in 38 Cases[J].Chinese Journal of Minimally Invasive Surgery,2017,17(5):418-421.
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诺舒治疗异常子宫出血38例()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
17
期数:
2017年5期
页码:
418-421
栏目:
临床研究
出版日期:
2017-07-14

文章信息/Info

Title:
NovaSure for Abnormal Uterine Bleeding in 38 Cases
作者:
袁博; 王武亮**; 邓克红; 赵玉芝
郑州大学第二附属医院妇科，郑州450014
Author(s):
Yuan Bo;  Wang Wuliang;  Deng Kehong;  et al.
Department of Gynecology, Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, China
关键词:
诺舒; 子宫内膜去除术; 异常子宫出血; 合并症
Keywords:
NovaSure; Endometrial ablation; Abnormal uterine bleeding; Complication
文献标志码:
A
摘要:
目的探讨诺舒治疗异常子宫出血的疗效。方法2013年1月~2016年1月，因异常子宫出血行诺舒阻抗子宫内膜去除术38例，其中合并严重内科疾病22例（57.9%）。先行宫腔镜检查，评估宫腔情况，并取子宫内膜活检，待常规病理排除子宫内膜恶性病变后行宫腔镜诺舒阻抗子宫内膜去除术，术后门诊或电话随访，观察月经、血红蛋白改善及并发症情况。术后闭经、点滴出血、少量月经、正常月经认定为临床治疗有效。结果38例均顺利完成手术，诺舒治疗时间66~122 s，（89.5±24.5）s，术中出血均<30 ml，术中术后均无严重并发症发生。二次手术率5.3%（2/38）。术后3、6、12、36个月有效率分别为100%（37/37）、100%（29/29）、100%（24/24）、100%（8/8）；闭经率分别为62.2%（23/37）、69.0%（20/29）、750%（18/24）、87.5%（7/8）；满意率为97.3%（36/37）、96.6%（28/29）、100%（24/24）、100%（8/8）。术后3个月贫血纠正率为54.1％（20/37）（1例因原发病死亡）。32例非血液系统疾病患者术前血红蛋白为（84.37±21.58）g/L，术后3个月升高至（105.21±10.43）g/L（配对t检验，t=17.092,P=0.000）。结论诺舒操作简单，安全，微创，效果好，患者满意率高，特别适用于合并严重内科疾病无法采用药物及子宫切除术的患者。
Abstract:
ObjectiveTo explore the effect of the second-generation endometrial ablation treatment (NovaSure) for abnormal uterine bleeding.MethodsFrom January 2013 to January 2016, a total of 38 patients with abnormal uterine bleeding accepted the NovaSure procedure, with 22 patients accompanied with severe co-mobidities. All the patients accepted hysteroscopy preoperatively for uterine cavity evaluation and endometrial biopsy. After excluding endometrial malignant lesions, endometrial ablation by NovaSure technology was carried out. The patients were followed up with out-patient or telephone postoperatively to observe the curative effect, complications and the improvement of menstruation and hemoglobin. Postoperative menstrual volume described as amenorrhea, spotting bleeding, a small amount of menstruation and normal menstruation was identified as effectiveness.ResultsThe surgery was successfully completed in all the 38 cases. The treatment time was 66-122 s (mean, 89.5±24.5 s). The intraoperative bleeding was less than 30 ml, with no serious complications occurred during the operation. Two of 38 patients required an additional surgery during the follow-up period. At postoperative 3 months, 6 months, 12 months, and 36 months, the effective rates of menstrual improvement were 100% (37/37), 100% (29/29), 100% (24/24), and 100% (8/8); the rates of amenorrhea were 62.2% (23/37), 69.0% (20/29), 75.0% (18/24), and 87.5% (7/8); the satisfaction rates of operation were 97.3% (36/37), 96.6% (28/29), 100% (24/24), and 100% (8/8), respectively. At 3 months after operation, the anemia was improved in 54.1% patients (20/37). In 32 patients with non-blood systemic diseases, the preoperative hemoglobin was 84.37±21.58 g/L, which was increased to 105.21±10.43 g/L at 3 months postoperatively (t=17.092, P=0.000).ConclusionThe second-generation endometrial ablation procedure is simple, safe, minimally invasive, and effective, with a high rate of patient satisfaction especially for those with severe co-mobidities who can not be tolerant to drugs or hysterectomy.

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备注/Memo

备注/Memo:
基金项目：河南省卫生厅科技攻关普通项目（项目编号：201503086）**通讯作者，E-mail：wangwuliang888@sina.com
更新日期/Last Update: 2017-07-14