[1]宋鹏远 孙亚红** 郭亚 盛立军①.微波消融与手术切除结直肠癌肝转移的疗效比较[J].中国微创外科杂志,2015,15(10):887-890.
　Song Pengyuan,Sun Yahong,Guo Ya,et al.Microwave Ablation Versus Surgical Resection of Colorectal Cancer Liver Metastasis: Comparison of Clinical Efficacy[J].Chinese Journal of Minimally Invasive Surgery,2015,15(10):887-890.
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微波消融与手术切除结直肠癌肝转移的疗效比较()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
15
期数:
2015年10期
页码:
887-890
栏目:
临床论著
出版日期:
2015-10-20

文章信息/Info

Title:
Microwave Ablation Versus Surgical Resection of Colorectal Cancer Liver Metastasis: Comparison of Clinical Efficacy
作者:
宋鹏远 孙亚红** 郭亚 盛立军①
（山东省医学科学院附属医院内五科，济南250031）
Author(s):
Song Pengyuan;  Sun Yahong;  Guo Ya;  et al.
Fifth Department of Internal Medicine, Affiliated Hospital of Shandong Academy of Medical Sciences, Jinan 250031, China
关键词:
微波消融; 手术切除; 结直肠癌; 肝转移
Keywords:
Microwave ablation; Surgical resection; Colorectal cancer; Liver metastasis
分类号:
R735
文献标志码:
A
摘要:
目的比较结直肠癌肝转移瘤行微波消融(microwave ablation，MA)与肝切除手术治疗的疗效。方法回顾性分析2010年10月～2014年2月62例结直肠癌肝转移，其中肝转移灶MA治疗28例（MA组），手术切除34例（手术组），比较2组无病生存期（DFS）、生存期（OS）、并发症、住院时间及费用。结果MA组住院时间（5.9±0.9）d，显著短于手术组（11.8±6.9）d（t=-4.487，P=0.001）；MA组治疗费用（2.9±0.5）万元，显著少于手术组（5.5±0.8）万元（t=14.949，P=0000）；MA组重度并发症发生率0，显著低于手术组26.5%（9/34）（Fisher’s检验，P=0.003）。MA组与手术组累积无病生存率差异无统计学意义（log-rank χ2检验: χ2=2.010，P=0.156）；MA组与手术组累积生存率差异无统计学意义（log-rank χ2检验: χ2=0.307，P=0.580）。结论MA治疗结直肠癌肝转移微创、经济、安全有效，治疗效果不逊于手术治疗。
Abstract:
ObjectiveTo compare the efficacy of microwave ablation (MA) and surgical resection of colorectal cancer liver metastasis. MethodsA retrospective analysis was made on 62 cases of colorectal cancer liver metastasis from October 2010 to February 2014, including 28 cases of MA treatment and 34 cases of surgical resection. Comparison was conducted between the two groups on disease-free survival (DFS), overall survival (OS), severe complications, hospitalization time and expenses.ResultsThe hospitalization time in the MA group (5.9±0.9 d) was significantly shorter than that in the surgery group (11.8±6.9 d, t=-4.487, P=0.001). In the MA group, the costs of treatment was 29000±5000 yuan, which was significantly less than that in the surgery group (55000±8000 yuan, t=14.949, P=0.000). No severe complications occurred in the MA group, which was significantly less than that in the surgical group (9/34, 26.5%, P=0.003). No significant difference was found in DFS (χ2=2010, P=0.156) or OS (χ2=0.307, P=0.580) between the two groups.ConclusionsMA for colorectal cancer liver metastasis is a minimally invasive, economical, safe and effective method. Its therapeutic effect is comparable to surgery treatment.

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备注/Memo

备注/Memo:
基金项目：山东省医学科学院面上项目（2012）年第6号**通讯作者，E-mail:sunyahong0915@163.com①(山东省肿瘤医院肿瘤科,济南250031)
更新日期/Last Update: 2016-02-03