[1]王笑茹　 张炎　 陈启新　 霍峰　 薛景凤.选择性手术显微镜下腮腺切除减少面瘫发生的实验研究[J].中国微创外科杂志,2001,01(4):247-248.
　Wang Xiaoru,Zhang Yan,Cheng Qixin,et al.Experimental study on reducing the morbidity of the facial paralysis after parotidectomy by selective microsurgery[J].Chinese Journal of Minimally Invasive Surgery,2001,01(4):247-248.
点击复制

选择性手术显微镜下腮腺切除减少面瘫发生的实验研究()
分享到：

《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
01
期数:
2001年4期
页码:
247-248
栏目:
基础研究
出版日期:
2001-04-30

文章信息/Info

Title:
Experimental study on reducing the morbidity of the facial paralysis after parotidectomy by selective microsurgery
作者:
王笑茹　 张炎　 陈启新　 霍峰　 薛景凤
承德医学院附属医院口腔科承德,067000
Author(s):
Wang Xiaoru;  Zhang Yan;  Cheng Qixin;  et al.
Department of Stomatology. ofAffiliated Hospital, Chengde Medical College, city ofChengde067000, China.
关键词:
腮腺 显微外科 面神经
Keywords:
Parotid gland　　Microsurgery　　Facial nerve　　Neuronal soma　　lschemia
分类号:
R65
文献标志码:
A
摘要:
目的探讨保护神经外血管系,减少神经局部缺血造成面神经核细胞逆行性变性所致面瘫的途径.方法选用健康家兔,采用自体对照方法,模拟人腮腺全切术.实验侧在手术显微镜下游离面神经切除腮腺,保护神经外血管系.对照侧镜下完成相同手术,但破坏神经外血管系.15只兔分为三组,术后2、3、4周分别取面神经核光镜下观察.结果实验侧术后面瘫症状轻微,发生率低.对照侧面瘫显著.术后4周对照侧面神经核细胞数少于实验侧(P＜0.05).结论手术显微镜下解剖面神经切除腮腺,保护外血管系,可减少因神经局部缺血造成的面瘫.
Abstract:
Objective　To reduce the morbidity of facial paralysis because of ischemia of the facial nerve led to retrograde degeneration of the neuronal soma.　Methods　Health rabbits were collected for the parotidectomy as that of on the same rabbit. Capillary net on the facial neverwere protected from damaging on the experiment sidewhen excising parotid glands and dissecting facial never by surgical microscope. The same operation were performed on the control side, however, the capillary net on it were completely destructed. Fifteen rabbits were divided into three groups. The neuronal soma of ficial nerve in brain tissue were stained and observed under optic microscope at 2,3,4 weeks after operation.　Results　Both of symptom and morbidity of the facial paralysis on the experiment side were lower than that on the control sides. The number of neuronal soma on the control sideswas less than that on the exper- iment sides (P<0.05).　Conclusions　The study indicated that morbidity of facial paralysis descend because cap- illary net on the facial nervewere avoided of damagingwhen excising parotid glands and anatomying facil never by sur- gical microscope.

参考文献/References:

［1］Nishida M, Matsuura H. A landmark for facial nerve identification during parotid surgery. J Oral Maxillofac Surg, 1993, 51:451-453.
［2］Cmillan A S, Jablonsk N G, McMillofac D R. The position and branching pattern of the facial nerve and their effect on transcutaneous electrical stimulation in orofacial rgeion. Oral surg, 1987, 63:539-541.
［3］游士奇.保留面神经腮腺切除术113例报告.口腔医学,1983,3:22-23.
［4］Nukada H, Mcmorran PD. Perivascular demyelination and intramyelinic oedema in reperfusion never injury. J Anat, 1994, 185:259-266.
［5］李树玲编著,头颈部肿瘤诊断、治疗及预后.天津:天津科技出版社,1993.130.
［6］孔吉明,钟世镇,胡耀民.周围神经损伤所致感觉神经胞体死亡的保护.解剖学杂志,1994,17(增刊):180.
［7］薛景凤,张炎,张昆.大鼠坐骨神经局部缺血所致神经元胞体超微结构的病理变化.解剖学杂志,1996,19:502-504.
［8］薛景凤,张炎,张昆.大鼠坐骨神经局部缺血对轴浆运输影响.解剖学杂志,1998,21:325-328.

更新日期/Last Update: 2014-09-26