[1]邓露丝郑莹**杨帆王乔王平杨小芸潘小玲李征宇綦小蓉.经脐单孔腹腔镜技术治疗妇科恶性肿瘤363例[J].中国微创外科杂志,2025,01(7):385-392.
　Deng Lusi,Zheng Ying,Yang Fan,et al.Transumbilical Laparoendoscopic Singlesite Surgery in the Treatment of 363 Patients With Gynecologic Malignant Neoplasms[J].Chinese Journal of Minimally Invasive Surgery,2025,01(7):385-392.
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经脐单孔腹腔镜技术治疗妇科恶性肿瘤363例()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
01
期数:
2025年7期
页码:
385-392
栏目:
临床论著
出版日期:
2025-07-30

文章信息/Info

Title:
Transumbilical Laparoendoscopic Singlesite Surgery in the Treatment of 363 Patients With Gynecologic Malignant Neoplasms
作者:
邓露丝郑莹**杨帆王乔王平杨小芸潘小玲李征宇綦小蓉
(四川大学华西第二医院妇产科出生缺陷与相关妇儿疾病教育部重点实验室，成都610041)
Author(s):
Deng Lusi;  Zheng Ying;  Yang Fan;  et al.
Department of Gynecology, Key Laboratory of Birth Defects and Related Maternal and Child Diseases of Ministry of Education, West China Second Hospital, Sichuan University, Chengdu 610041, China
关键词:
腹腔镜手术; 单孔腹腔镜手术; 妇科恶性肿瘤
Keywords:
Laparoscopy; Laparoendoscopic singlesite surgery; Gynecological malignant neoplasms
文献标志码:
A
摘要:
目的探讨经脐单孔腹腔镜手术(transumbilical laparoendoscopic singlesite surgery，TULESS)治疗妇科恶性肿瘤的可行性和安全性。方法回顾性分析2017年11月~2021年10月TULESS治疗妇科三大恶性肿瘤363例资料，其中子宫内膜癌123例(机器人4例)，宫颈癌211例(机器人16例)，卵巢癌29例(机器人1例)。观察手术指标、术后恢复指标和肿瘤学指标。结果①可行性：子宫内膜癌、宫颈癌、卵巢癌中转率分别为3.3%(4/123)、4.3%(9/211)、6.9%(2/29)，手术时间分别为(213.8±64.3)min、(288.8±85.6)min、(307.0±73.6)min。②安全性：子宫内膜癌、宫颈癌、卵巢癌中位术中出血量分别为50(50，100)ml、100(50，200)ml、100(65，325)ml，术中并发症发生率分别为3.3%(4/123)、4.7%(10/211)、172%(5/29)，术后近期(12周内)并发症发生率分别为7.3%(9/123)、11.4%(24/211)、17.2%(5/29)；中位随访时间分别为42.1(23.3，69.6)月、41.5(23.3，70.6)月、39.9(23.1，65.5)月，5年无病生存率(diseasefree survival，DFS)分别为92.3%、93.3%、84.4%，5年总生存率(overall survival，OS)分别为96.8%、94.5%、88.5%。结论TULESS治疗妇科恶性肿瘤具有可行性、安全性。
Abstract:
ObjectiveTo explore the feasibility and safety of transumbilical laparoendoscopic singlesite surgery (TULESS) in the treatment of gynecologic malignant neoplasms.MethodsThe data of 363 patients with gynecologic malignant neoplas from November 2017 to October 2021 were collected for retrospective study. There were 123 cases of endometrial cancer ［4 cases of robotic TULESS (RTULESS)］, 211 cases of cervical cancer (16 cases of RTULESS), and 29 cases of ovarian cancer (1 case of RTULESS). Data collection included operationrelated characteristics, postoperative rehabilitation indicators and oncological outcomes.Results①Feasibility: the surgical conversion rate of the three groups was 3.3% (4/123), 4.3% (9/211), and 6.9% (2/29), and the average operation duration was (213.8±64.3) min, (288.8±85.6) min, and (307.0±736) min, respectively. ②Safety: the median value of blood loss during surgery of the three groups was 50 (50, 100) ml, 100 (50, 200) ml, and 100 (65, 325) ml, the intraoperative complications rate was 3.3% (4/123), 4.7% (10/211), and 17.2% (5/29), the postoperative complications rate was 7.3% (9/123), 11.4% (24/211), and 17.2% (5/29), the median follow up time was 421 (23.3, 69.6) months, 41.5 (23.3, 70.6) months, and 39.9 (23.1, 65.5) months, the fiveyear diseasefree survival (DFS) was 92.3%, 93.3%, and 844%, and the fiveyear overall survival (OS) was 96.8%, 94.5%, and 88.5%, respectively.ConclusionTULESS is a safe and feasible approach for the treatment of gynecologic malignant neoplasms.

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备注/Memo

备注/Memo:
基金项目：国家重点研发计划资助(2022YFC2704103)；四川省科技厅重点研发项目 (23ZDYF1628)**通讯作者，Email：zhy_chd@126.com
更新日期/Last Update: 2025-09-18