[1]单学敏 席思思 尚鶄 杨秀丽 薛晴**.腹腔镜卵巢内膜异位囊肿剥除术后卵巢低反应体外受精-胚胎移植的结局[J].中国微创外科杂志,2022,01(2):114-118.
　Shan Xuemin,Xi Sisi,Shang Jing,et al.Outcome Analysis of in vitro Fertilizationembryo Transfer in Patients With Ovarian Endometrial Cyst Combined With Poor Ovarian Response After Laparoscopic Cystectomy[J].Chinese Journal of Minimally Invasive Surgery,2022,01(2):114-118.
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腹腔镜卵巢内膜异位囊肿剥除术后卵巢低反应体外受精-胚胎移植的结局()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
01
期数:
2022年2期
页码:
114-118
栏目:
临床研究
出版日期:
2022-05-19

文章信息/Info

Title:
Outcome Analysis of in vitro Fertilizationembryo Transfer in Patients With Ovarian Endometrial Cyst Combined With Poor Ovarian Response After Laparoscopic Cystectomy
作者:
单学敏 席思思 尚鶄 杨秀丽 薛晴**
（北京大学第一医院妇产科，北京100034）
Author(s):
Shan Xuemin;  Xi Sisi;  Shang Jing;  et al.
Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing 100034, China
关键词:
卵巢低反应; 腹腔镜卵巢子宫内膜异位囊肿剥除术; 卵巢子宫内膜异位囊肿; 体外受精-胚胎移植; 妊娠结局
Keywords:
Poor ovarian response; Laparoscopic endometrioma cystectomy; Ovarian endometrial cyst; In vitro fertilizationembryo transfer; Pregnancy outcomes
文献标志码:
A
摘要:
目的比较腹腔镜卵巢子宫内膜异位囊肿（ovarian endometrial cyst，OEC）剥除术后卵巢低反应（poor ovary response，POR）与OEC未手术POR体外受精-胚胎移植（in vitro fertilizationembryo transfer，IVFET）的结局。方法回顾性分析2013年1月~2018年12月我科103例POR行IVFET的临床资料，其中72例OEC术后POR（OEC术后组），31例OEC未手术POR（OEC组），比较2组获卵数、成熟卵母细胞（MⅡ卵母细胞）数、优质胚胎数、临床妊娠率、活产率的差异。结果OEC术后组获卵数较OEC组明显减少 ［2（1，3）个vs. 3（2，4）个,Z=-2.297, P=0022］，MⅡ卵母细胞数显著减少 ［1（1，2）个vs. 2（1，3）个,Z=-2.130，P=0.033］，优质胚胎数显著减少［0（0，1）个vs. 1（0，2）个，Z=-2.000,P=0045］。2组临床妊娠率［17.6%(6/34)vs.27.8%(5/18), χ2=0244，P=0621］、活产率［88%(3/34)vs167%(3/18), χ2=0149，P=0699］差异无显著性。OEC术后组早期流产率333%（2/6)，OEC组200%（1/5)。结论腹腔镜OEC剥除术后POR患者IVFET结局不良。
Abstract:
ObjectiveTo compare outcomes of in vitro fertilizationembryo transfer (IVFET) in patients with ovarian endometrial cyst (OEC) combined with poor ovarian response (POR) after laparoscopic cystectomy and patients with OEC without operation.MethodsThis retrospective study included 103 patients with POR who underwent IVFET in our department from January 2013 to December 2018. Among them, 72 cases were OEC postoperative POR (OEC postoperative group) and 31 cases were OEC unoperated POR (OEC group). The differences in the number of retrieved oocytes, MⅡ oocytes, high quality embryos, clinical pregnancy rate, early abortion rate and live birth rate between the two groups were compared.ResultsThe number of retrieved oocytes in the OEC postoperative group was lower, and the difference was statistically significant ［2 (1, 3) vs. 3 (2, 4), Z=-2.297, P=0.022］. The number of MⅡ oocytes significantly decreased ［1 (1, 2) vs. 2 (1, 3), Z=-2.130, P=0.033］. The number of high quality embryos significantly decreased ［0 (0, 1) vs. 1 (0, 2), Z=-2.000, P=0.045］. There was no significant difference in clinical pregnancy rate ［17.6% (6/34) vs. 27.8% (5/18), χ2=0.244,P=0.621］ and live birth rate ［8.8% (3/34) vs. 16.7% (3/18), χ2=0.149,P=0.699］ between the two groups. The early abortion rate was 33.3% (2/6) in the OEC postoperative group and 20.0% (1/5) in the OEC group. ConclusionPatients with poor ovarian response after laparoscopic ovarian endometrioma cystectomy has a poor IVFET outcome.

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备注/Memo

备注/Memo:
基金项目：国家自然科学基金重大研发计划培育项目（91949113）**通讯作者，Email:13601038626@163.com
更新日期/Last Update: 2022-05-19