[1]崔澍 许长宝** 赵兴华 褚校涵 谷清阳.Allium覆膜输尿管支架治疗良恶性输尿管狭窄20例[J].中国微创外科杂志,2021,01(10):889-893.
　Cui Shu,Xu Changbao,Zhao Xinghua,et al.Allium Ureteral Stent for Treatment of Benign and Malignant Ureteral Stricture: a Report of 20 Cases[J].Chinese Journal of Minimally Invasive Surgery,2021,01(10):889-893.
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Allium覆膜输尿管支架治疗良恶性输尿管狭窄20例()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
01
期数:
2021年10期
页码:
889-893
栏目:
临床研究
出版日期:
2021-10-25

文章信息/Info

Title:
Allium Ureteral Stent for Treatment of Benign and Malignant Ureteral Stricture: a Report of 20 Cases
作者:
崔澍 许长宝** 赵兴华 褚校涵 谷清阳
（郑州大学第二附属医院泌尿外科，郑州450000）
Author(s):
Cui Shu;  Xu Changbao;  Zhao Xinghua;  et al.
Department of Urology, Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China
关键词:
良恶性输尿管狭窄; Allium覆膜输尿管支架; 输尿管支架症状调查问卷
Keywords:
Benign and malignant ureteral stricture; Allium ureteral stent; Ureteral stent symptoms questionnaire
文献标志码:
A
摘要:
目的探讨Allium覆膜输尿管支架治疗良恶性输尿管狭窄的安全性和有效性。 方法输尿管镜经尿道逆行置入Allium覆膜输尿管支架，逆行造影检查确认支架位置正常，输尿管通畅。术后每6个月复查血常规、血肌酐、血尿素氮、腹部平片、泌尿系彩超等。结果手术时间(96.8±31.1)min，术后住院时间（3.0±1.1）d。术后6个月肾盂宽度较术前均显著降低［（1.9±1.3）cm vs. (2.7±1.0)cm,t=8.707,P=0.000］；术后6个月血肌酐中位数较术前均显著降低［84.0（61.0～312.0)μmol/L vs. 93.0（57.0～354.0）μmol/L ,Z=-2.167,P=0.030］；术后6个月输尿管支架症状调查问卷（Ureteral Stent Symptoms Questionnaire，USSQ）总分明显低于术前［(83.2±8.9)分vs.(99.3±9.6)分，t=12.546，P=0.000］。术后6个月中位血尿素氮与术前差异无统计学意义［6.2（5.0～10.8）mmol/L vs. 6.3（4.9～11.1）mmol/L，Z=-0.224，P=0.823］。20例中位随访时间11(9～14)个月，4例出现支架相关并发症，药物保守治疗后好转。20例输尿管支架均保持通畅，1例术后6个月发现支架移位至膀胱，为中段狭窄，复查肾积水加重，重新置入支架后未再出现移位。结论Allium覆膜输尿管支架治疗良恶性输尿管狭窄安全、有效，能长期留置并且保持较高的输尿管通畅率和较低的并发症发生率，支架移位为主要并发症。
Abstract:
ObjectiveTo evaluate the safety and efficacy of the Allium ureteral stent for treating benign and malignant ureteral stricture.MethodsThe Allium ureteral stent was placed retrogradely transurethrally with a ureteroscope, and a retrograde contrast examination was carried out to confirm normal stent position and ureteral patency. After the operation, the blood routine, blood creatinine, urea nitrogen, abdominal plain film, and urinary color ultrasound were reviewed every 6 months.ResultsThe operative time was (96.8±31.1) min, and the postoperative hospital stay was (3.0±1.1) d. The renal pelvis width was significantly lower at 6 months after surgery compared with preoperation ［(1.9±1.3) cm vs. (2.7±1.0) cm, t=8.707, P=0.000］. The median serum creatinine was significantly lower at 6 months after surgery compared with preoperation ［84.0 (61.0-312.0) μmol/L vs. 930 (57.0-354.0) μmol/L, Z=-2.167, P=0.030］. The Ureteral Stent Symptoms Questionnaire total score at 6 months after surgery was significantly lower compared with preoperation ［(83.2±8.9) points vs. (99.3±9.6) points, t=12.546, P=0.000］ whereas the median blood urea nitrogen concentration at 6 months after surgery was not significantly different from preoperation ［6.2 (5.0-10.8) mmol/L vs. 6.3 (4.9-11.1) mmol/L, Z=-0.224, P=0.823］. With a median followup time of 11 (9-14) months in 20 patients, 4 patients experienced stentrelated complications, which were improved after conservative medical treatment. All the 20 ureteral stents remained patent. One patient was found to have stent migration to the bladder 6 months after operation, which was middle stricture. The hydronephrosis was aggravated after reexamination, and there was no displacement after reimplantation of the stent.ConclusionsThe Allium ureteral stent for the treatment of benign and malignant ureteral strictures is safe and effective. It can stay in place for a long time and maintain a high ureteral patency rate with a low complication rate. Stent migration is a major complication.

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备注/Memo

备注/Memo:
基金项目：河南省医学科技攻关计划省部共建项目（SBGJ2018045）**通讯作者，Email：xcb1966@126.com
更新日期/Last Update: 2022-02-08