[1]王晨 蒋建发**.射频子宫内膜消融术治疗再生障碍性贫血患者异常子宫出血的疗效[J].中国微创外科杂志,2021,01(4):333-335.
　Wang Chen,Jiang Jianfa..Effect of Radiofrequency Endometrial Ablation for Abnormal Uterine Bleeding in Patients With Aplastic Anemia[J].Chinese Journal of Minimally Invasive Surgery,2021,01(4):333-335.
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射频子宫内膜消融术治疗再生障碍性贫血患者异常子宫出血的疗效()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
01
期数:
2021年4期
页码:
333-335
栏目:
临床研究
出版日期:
2021-04-25

文章信息/Info

Title:
Effect of Radiofrequency Endometrial Ablation for Abnormal Uterine Bleeding in Patients With Aplastic Anemia
作者:
王晨 蒋建发**
（中南大学湘雅三医院妇科，长沙410013）
Author(s):
Wang Chen;  Jiang Jianfa.
Department of Gynecology, Third Xiangya Hospital of Central South University, Changsha 410013, China
关键词:
再生障碍性贫血; 异常子宫出血; 射频子宫内膜消融术
Keywords:
Aplastic anemia; Abnormal uterine bleeding; Radiofrequency endometrial ablation
文献标志码:
A
摘要:
目的探讨射频子宫内膜消融术治疗再生障碍性贫血患者异常子宫出血的疗效及安全性。方法回顾性分析2014年2月~2020年4月射频子宫内膜消融术（诺舒）治疗21例异常子宫出血合并再生障碍性贫血患者的临床资料，血红蛋白21~87 g/L，其中中度贫血11例，重度贫血9例，极重度贫血1例。白细胞（1.32~6.6）×109/L，血小板（4~59）×109/L。结果均顺利完成手术，消融时间（59.2±19.3）s，术中中位出血量15（5~20）ml。无子宫穿孔、过度水化综合征、周围脏器损伤等严重并发症发生。1例术后2小时大量阴道流血，予宫缩剂治疗后止血。中位随访时间46（4~77）个月，19例闭经，2例有点滴出血。闭经率90.5%，有效率100%。结论射频子宫内膜消融术可有效治疗再生障碍性贫血患者异常子宫出血，无严重手术并发症。
Abstract:
ObjectiveTo investigate the efficacy and safety of radiofrequency endometrial ablation in the treatment of abnormal uterine bleeding in patients with aplastic anemia.MethodsClinical data of 21 patients with abnormal uterine bleeding complicated with aplastic anemia treated by radiofrequency endometrial ablation from February 2014 to April 2020 were retrospectively analyzed. The preoperative hemoglobin was 21-87 g/L, including 11 cases of moderate anemia, 9 cases of severe anemia and 1 case of extremely severe anemia. The white blood cells level of the patients were (1.32-6.6)×109/L and platelets level were (4-59)×109/L.ResultsAll the operations were successfully completed, with an average ablation time of (59.2±19.3) s. The median intraoperative blood loss was 15 ml (range, 5-20 ml). No severe complications such as uterine perforation, hyperhydration syndrome or peripheral organ injury occurred. One patient showed massive vaginal bleeding 2 hours after the operation, which was improved after hysterotonics treatment. The patients were followed up for 4-77 months （median,46 months) after operation. There were 19 patients with amenorrhea and only 2 patients with spotting bleeding. The amenorrhea rate was 90.5% and the effective rate was 100%.ConclusionAbnormal uterine bleeding in patients with aplastic anemia can be effectively treated by radiofrequency endometrial ablation without serious surgical complications.

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备注/Memo

备注/Memo:
基金项目：国家自然科学基金（81801422）**通讯作者，Email：670561033@qq.com
更新日期/Last Update: 2021-06-30