[1]侯征 牛子儒 姚颖 王莎 韩劲松 郭红燕 贺豪杰*.手术相关女性慢性盆腔痛的病因及诊治分析[J].中国微创外科杂志,2021,01(1):31-35.
 Hou Zheng,Niu Ziru,Yao Ying,et al.Clinical Analysis of Causes and Treatment of Chronic Pelvic Pain in Postsurgical Female Patients[J].Chinese Journal of Minimally Invasive Surgery,2021,01(1):31-35.
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手术相关女性慢性盆腔痛的病因及诊治分析()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
01
期数:
2021年1期
页码:
31-35
栏目:
临床研究
出版日期:
2021-02-26

文章信息/Info

Title:
Clinical Analysis of Causes and Treatment of Chronic Pelvic Pain in Postsurgical Female Patients
作者:
侯征 牛子儒 姚颖 王莎 韩劲松 郭红燕 贺豪杰*
(北京大学第三医院妇产科,北京100191)
Author(s):
Hou Zheng Niu Ziru Yao Ying et al.
Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China
关键词:
慢性盆腔痛术后慢性疼痛阴部神经痛神经阻滞加巴喷丁
Keywords:
Chronic pelvic painChronic postsurgical painPudendal neuralgiaNerve blockGabapentin
文献标志码:
A
摘要:
目的探讨女性术后慢性盆腔痛的病因、诊断流程及治疗方法。方法回顾性分析2019年7月~2020年6月我院诊治的60例术后慢性盆腔痛资料。根据病因进行个体化治疗,包括加巴喷丁、神经阻滞、抗生素、口服避孕药、手术、中成药等。疗效评价标准:①完全缓解,疼痛消失,视觉模拟评分(Visual Analogue Scale,VAS)降至0分;②部分缓解,疼痛减轻,VAS评分或疼痛频率降低≥50%;③无效,VAS评分及疼痛频率降低<50%。结果诊断神经病理性疼痛34例(56.7%),盆腔炎症性疾病11例(18.3%),子宫内膜异位症7例(11.7%),盆腔炎症性疾病合并神经病理性疼痛2例(3.3%),盆腔炎症性疾病合并子宫内膜异位症2例(3.3%),子宫内膜异位症合并神经病理性疼痛2例(3.3%),肠易激综合征1例(1.7%),原因不明1例(1.7%)。除5例因备孕未治疗外,55例治疗后随访1~9个月,平均2.6月。完全缓解18例,部分缓解34例,无效3例。有效率94.5%(52/55)。结论手术相关女性慢性盆腔痛可能的病因包括神经病理性疼痛、子宫内膜异位症、盆腔炎症性疾病,亦可能为消化系统或泌尿系统疾病,诊断过程中应仔细鉴别,针对病因进行个体化治疗。
Abstract:
ObjectiveTo investigate the etiology, evaluation and treatment of chronic pelvic pain in postsurgical female patients.MethodsClinical data of 60 postsurgical female patients with chronic pelvic pain from our clinic were collected between July 2019 and June 2020. Treatment was individualized according to evaluation, including gabapentin administration, nerve block, antibiotics, oral contraceptives, surgery, traditional Chinese medicine. The criteria of efficacy was defined as the followings: ①Complete response, pain disappeared, Visual Analogue Scale(VAS) score dropped to 0; ②Partial response, pain relief, VAS score or pain frequency decreased ≥50%; ③No response, VAS score or pain frequency decreased <50%.ResultsThere were 34 cases (56.7%) of neuropathic pain, 11 cases (18.3%) of pelvic inflammatory disease, 7 cases (11.7%) of endometriosis, 2 cases (33%) of pelvic inflammatory disease with concurrent neuropathic pain, 2 cases (3.3%) of pelvic inflammatory disease with concurrent endometriosis, 2 cases (3.3%) of endometriosis with concurrent neuropathic pain, 1 case (1.7%) of irritable bowel syndrome, and 1 case (1.7%) of unexplained chronic pelvic pain. Five cases were not treated due to pregnancy plan. Another 55 cases were followed up from 1 to 9 months after treatment, with an average of 2.6 months. We found complete response in 18 cases, partial response in 34 cases, and no response in 3 cases, with an effective rate of 94.5% (52/55).ConclusionsChronic pelvic pain in postsurgical women has complex etiology and may result from diseases such as neuropathic pain, endometriosis, pelvic inflammatory disease, digestive and urinary disease. Careful evaluation is key in guiding treatment.

参考文献/References:

[1]Jarrell JF,Vilos GA,Allaire C,et al.Consensus guidelines for the management of chronic pelvic pain.J Obstet Gynaecol Can,2005,27(9):869-910.
[2]Learman LA,McHugh WK.Chronic pelvic pain:ACOG Practice Bulletin,Number 218.Obstet Gynecol,2020,135(3):e98-e109.
[3]Latthe P,Latthe M,Say L,et al.WHO systematic review of prevalence of chronic pelvic pain:a neglected reproductive health morbidity.BMC Public Health,2006,6:177.
[4]Lou WJ,Chen B,Zhu L,et al.Prevalence and factors associated with female sexual dysfunction in Beijing,China.Chin Med J,2017,130(12):1389-1394.
[5]Cheong Y,Stone RW.Chronic pelvic pain:aetiology and therapy.Best Pract Res Clin Obstet Gynaecol,2006,20(5):695-711.
[6]贺豪杰,郭红燕.慢性盆腔痛的临床评估及诊断流程.实用妇产科杂志,2016,32(5):323-325.
[7]Labat JJ,Riant T,Robert R,et al.Diagnostic criteria for pudendal neuralgia by pudendal nerve entrapment (Nantes criteria).Neurourol Urodyn,2008,27(4):306-310.
[8]中华医学会妇产科学分会感染性疾病协作组.盆腔炎症性疾病诊治规范(2019修订版).中华妇产科杂志,2019,54(7):433-437.
[9]陈娟,朱兰.慢性盆腔痛的分类.实用妇产科杂志,2016,32(5):321-323.
[10]张立双,杨丰文,张俊华,等.桂枝茯苓胶囊/丸治疗慢性盆腔炎性疾病临床随机对照试验的系统评价.中国中药杂志,2017,42(8):1500-1509.
[11]Zhang D,Liu Z,Lin H,et al.Effectiveness of Honghua Ruyi Wan combined with antibiotics for relief of pelvic inflammatory disease in women.Biomed Res,2017,28(10):4665-4670.
[12]谢幸,孔北华,段涛.妇产科学.第9版.北京:人民卫生出版社,2018.83.
[13]中华医学会消化病学分会胃肠功能性疾病协作组,中华医学会消化病学分会胃肠动力学组.中国肠易激综合征专家共识意见(2015年,上海).中华消化杂志,2016,36(5):299-312.
[14]Treede RD,Rief W,Barke A,et al.A classification of chronic pain for ICD11.Pain,2015,156:1003-1007.
[15]Glare P,Aubrey KR,Myles PS.Transition from acute to chronic pain after surgery.Lancet,2019,393(10180):1537-1546.
[16]贺豪杰,郭红燕,韩劲松,等.B超引导下神经阻滞治疗女性慢性盆腔痛.中国微创外科杂志,2016,16(12):1085-1088.
[17]李水清,刘晓光,韩海凤.慢性盆腔痛的药物治疗.实用妇产科杂志,2016,32(5):331-333.
[18]Horne AW,Vincent K,Hewitt CA,et al.Gabapentin for chronic pelvic pain in women (GaPP2):a multicentre,randomised,doubleblind,placebocontrolled trial.Lancet,2020,396(10255):909-917.
[19]倪兵.泌尿系源性慢性盆腔痛.中国疼痛医学杂志,2012,18(3):138-139.
[20]Koneti KK,Perfitt JS.Chronic pain management after surgery.Surgery(Oxford),2019,37(8):467-471.

备注/Memo

备注/Memo:
*通讯作者,Email:haojiehe@yahoo.com
更新日期/Last Update: 2021-04-02