[1]高永山** 张志杰① 付伟 张振明 董跃华 王大伟 杨燕君 姜伟华.单操作孔胸腔镜肺叶切除术治疗非小细胞肺癌的学习曲线[J].中国微创外科杂志,2020,01(11):972-976.
 Gao Yongshan*,Zhang Zhijie,Fu Wei*,et al.Learning Curve of Single Utility Port Videoassisted Thoracoscopic Surgery Lobectomy for Patients With Nonsmall Cell Lung Cancer[J].Chinese Journal of Minimally Invasive Surgery,2020,01(11):972-976.
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单操作孔胸腔镜肺叶切除术治疗非小细胞肺癌的学习曲线()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
01
期数:
2020年11期
页码:
972-976
栏目:
临床论著
出版日期:
2020-11-25

文章信息/Info

Title:
Learning Curve of Single Utility Port Videoassisted Thoracoscopic Surgery Lobectomy for Patients With Nonsmall Cell Lung Cancer
作者:
高永山** 张志杰① 付伟 张振明 董跃华 王大伟 杨燕君 姜伟华
(河北北方学院附属第一医院胸心外科,张家口075000)
Author(s):
Gao Yongshan* Zhang Zhijie Fu Wei* et al.
*Department of Thoracic and Cardiovascular Surgery, First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, China
关键词:
非小细胞肺癌单操作孔电视胸腔镜手术肺叶切除术学习曲线CUSUM分析
Keywords:
Nonsmall cell lung cancerSingle utility port Videoassisted thoracoscopic surgeryLobectomyLearning curveCUSUM analysis
文献标志码:
A
摘要:
目的探讨单操作孔胸腔镜肺叶切除术治疗非小细胞肺癌的学习曲线。方法回顾性分析2012年8月~2016年12月同一手术团队连续完成的单操作孔胸腔镜肺叶切除术治疗非小细胞肺癌120例资料,使用累积和(cumulative sum,CUSUM)方法分析其学习曲线,并对学习曲线不同阶段的手术时间、术中出血量、淋巴结清扫组数及个数、术后住院时间、中转开胸率、术后并发症发生率等进行比较。结果CUSUM学习曲线最佳拟合方程为y=-9.225+2.833x-0.01932x2-0.00003698x3,拟合优度R2=0.9475,拟合曲线在手术例数累积至第62例以后斜率变为负,以此为界将学习曲线划分为2个阶段,A阶段为学习提高阶段(n=62),B阶段为熟练掌握阶段(n=58)。B阶段手术时间、术中出血量、术后住院时间、中转开胸率及术后并发症发生率均优于A阶段(P<0.05),2个阶段淋巴结清扫组数、个数以及累积生存率差异均无显著性(P>005)。结论在地市级三甲医院条件下,开展单操作孔胸腔镜肺叶切除术治疗非小细胞肺癌的学习曲线为62例,时间跨度2年半。
Abstract:
ObjectiveTo explore the learning curve of single utility port videoassisted thoracoscopic surgery (VATS) lobectomy for patients with nonsmall cell lung cancer (NSCLC).MethodsWe retrospectively analyzed the clinical data of 120 consecutive patients with NSCLC who underwent single utility port complete VATS lobectomy by the same team from August 2012 to December 2016. The cumulative sum analysis (CUSUM) was used to study the learning curve of single utility port VATS lobectomy. The operating time, blood loss, number of dissected lymph nodes and nodal stations, postoperative hospital stay, rate of thoracotomy conversion and postoperative complications were compared. ResultsThe CUSUM learning curve were best modeled as a polynomial with equation: y=-9.225+2.833x-0.01932x2-0.00003698x3, with goodnessoffit test R2=0.9475. The fitting curve slope turned into negative at the 62nd case, and the learning curve were divided into learning stage (stage A, n=62) and mastery stage (stage B, n=58) with 62 cases as the cut off point. The operative time, blood loss, postoperative hospital stay, rate of thoracotomy conversion and postoperative complications in stage B was significantly better than that in stage A (all P<0.05). The two stages were similar in terms of the number of dissected lymph nodes and nodal stations, and cumulative overall survival rates (all P>0.05).ConclusionLearning curve of single utility port VATS lobectomy for patients with NSCLC is approximately 62 cases and the time span of 2.5 years in municipal hospitals.

参考文献/References:

[1]赵云鹏,丛波,赵小刚,等.全胸腔镜肺叶切除术与开胸肺叶切除术淋巴结清扫及生存的meta分析.中华胸心血管外科杂志,2014,30(8):467-472.
[2]MartinUcar AE,Aragon J,Bolufer Nadal S,et al.The influence of prior multiport experience on the learning curve for singleport thoracoscopic lobectomy: a multicentre comparative study.Eur J Cardiothorac Surg,2017,51(6):1183-1187.
[3]Chen K,Wang X,Yang F,et al.Propensitymatched comparison of videoassisted thoracoscopic with thoracotomy lobectomy for locally advanced nonsmall cell lung cancer.J Thorac Cardiovasc Surg,2017,153(4):967-976.e2.
[4]初向阳,薛志强,张连斌,等.单操作孔胸腔镜肺叶切除术的初步报道.中国肺癌杂志,2010,13(1):19-21.
[5]刘煜,宋雪冰,张午临.单操作孔完全胸腔镜与传统三孔胸腔镜治疗肺癌的疗效比较.中国微创外科杂志,2018,18(3):205-208.
[6]Ye Z,Zhang B,Chen Y,et al.Comparison of single utility port videoassisted thoracoscopic surgery (VATS) and threeport VATS for nonsmall cell lung cancer.Oncol Lett,2019,18(2):1311-1317.
[7]支修益,石远凯,于金明.中国原发性肺癌诊疗规范(2015年版).中华肿瘤杂志,2015,37(1):67-78.
[8]高永山,薛占霞,董跃华,等.单操作孔胸腔镜治疗早期周围型非小细胞肺癌.中国胸心血管外科临床杂志,2016,23(12):1132-1135.
[9]秦倩,时飞宇,孙祺,等.达芬奇机器人手术系统辅助胃癌根治术的学习曲线.中华消化外科杂志,2019,18(5):459-465.
[10]蒲强,刘伦旭,车国卫,等.单向式全胸腔镜肺癌切除术的学习曲线分析.中华外科杂志,2010,48(15):1161-1165.
[11]柯宏刚,徐明明,严煜,等.单操作孔全胸腔镜肺叶切除学习曲线分析.中国内镜杂志,2015,21(12):1237-1241.
[12]Li X,Wang J,Ferguson MK.Competence versus mastery:the time course for developing proficiency in videoassisted thoracoscopic lobectomy.J Thorac Cardiovasc Surg,2014,147(4):1150-1154.
[13]廖虎,梅建东,刘成武,等.中国三级医院胸外科学科临床发展现状的调查研究.中华外科杂志,2018,56(12):888-891.
[14]王光宇,初向阳,李国,等.单操作孔电视胸腔镜肺叶切除术的学习曲线研究.中国医药,2014,9(5):642-644.
[15]吕静,文智,孙小康,等.市级医院环境下早期肺癌全胸腔镜肺叶切除的学习曲线探索.西南军医,2018,20(4):459-462.
[16]Tong C,Li T,Huang C,et al.Risk factors and impact of conversion to thoracotomy from 20,565 cases of thoracoscopic lung surgery.Ann Thorac Surg,2020,109(5):1522-1529.
[17]Sezen CB,Bilen S,Kalafat CE,et al.Unexpected conversion to thoracotomy during thoracoscopic lobectomy:a singlecenter analysis.Gen Thorac Cardiovasc Surg,2019,67(11):969-975.
[18]王毅,杨彦辉,罗雷,等.市级医院胸腔镜微创技术治疗胸部疾病.中国胸心血管外科临床杂志,2017,24(9):725-729.
[19]Zhong WZ,Liu SY,Wu YL.Numbers or stations:from systematic sampling to individualized lymph node dissection in nonsmallcell lung cancer.J Clin Oncol,2017,35(11):1143-1145.
[20]Lee PC,Kamel M,Nasar A,et al.Lobectomy for nonsmall cell lung cancer by videoassisted thoracic surgery: effects of cumulative institutional experience on adequacy of lymphadenectomy.Ann Thorac Surg,2016,101(3):1116-1122.

备注/Memo

备注/Memo:
基金项目:张家口市科技局指导项目(1921033D)**通讯作者,Email:gaoyongshan3333@163.com ①(中国人民解放军陆军第八十一集团军医院放射科,张家口075000)
更新日期/Last Update: 2021-02-07