[1]李保国①,陆敏②,王国良,等.619例肾脏肿瘤的临床病理特征分析[J].中国微创外科杂志,2018,18(5):445-449.
　Li Baoguo,Lu Min,Wang Guoliang*,et al.Pathological Characteristics Investigation of 619 Cases of Renal Tumors[J].Chinese Journal of Minimally Invasive Surgery,2018,18(5):445-449.
点击复制

619例肾脏肿瘤的临床病理特征分析()
分享到：

《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
18
期数:
2018年5期
页码:
445-449
栏目:
病理学研究
出版日期:
2018-09-04

文章信息/Info

Title:
Pathological Characteristics Investigation of 619 Cases of Renal Tumors
作者:
李保国①; 陆敏②; 王国良; 黄毅; 马潞林*
北京大学第三医院泌尿外科，北京100191
Author(s):
Li Baoguo;  Lu Min;  Wang Guoliang*;  et al.
*Department of Urology, Peking University Third Hospital, Beijing 100191, China
关键词:
肾脏肿瘤; 发病特点; 病理特点
Keywords:
Renal tumor; Epidemiology features; Pathological features
文献标志码:
A
摘要:
目的探讨肾脏肿瘤的发病特征、病理类型，为临床肾脏肿瘤诊治提供参考。方法回顾分析2015年1月~2016年12月北京大学第三医院泌尿外科619例肾脏肿瘤的临床资料，对患者年龄、性别、肿瘤部位、大小及病理分型等进行分析。结果肾良性肿瘤96例，女性占68.8%（66/96），男性占31.2%(30/96)，以血管平滑肌脂肪瘤为主（75例，781%），嗜酸细胞瘤13例 (13.5%)。恶性肿瘤523例，男性占69.0%（361/523），女性占31.0%（162/523），主要为肾透明细胞癌439例(83.9%)，乳头状肾细胞癌28例 (5.3%)，肾嫌色细胞癌26例（5.0%）。结论目前肾脏肿瘤患者中良性肿瘤构成有所上升，常见良恶性肿瘤病理分型及好发性别均无明显变化，但良恶性肿瘤均具有发病年龄提前及体积小型化的趋势，应制定相应的措施进行早期筛查与防治。
Abstract:
ObjectiveTo investigate pathological features and epidemiology of renal tumors, and to provide guidance for diagnosis and treatment. MethodsA total of 619 renal tumor patients were collected from January 2015 to December 2016 in this department. Patient’s age and gender, as well as tumor’s location, size, and pathological type were collected and analyzed.ResultsThere were 96 cases of benign renal tumors, including 30 males (31.2%) and 66 females (68.8%). The vascular leiomyoma (75 cases, 78.1%) and oncocytoma (13 cases, 13.5%) accounted for the majority. Renal malignancy was found in 523 cases, including 361 males (69.0%) and 162 females (31.0%), which mainly consisted of 439 cases of clear cell carcinoma (83.9%), 28 cases of papillary carcinoma (5.3%), and 26 cases of chromophobe cell carcinoma (5.0%).ConclusionsThe overall percentage of benign renal tumors has increased, but no obvious changes in pathological features and sex ratio of benign or malignant renal tumors has been found as compared to previous studies. The epidemiology of renal benign and malignant tumors has a tendency of early onset and small size. Thus some measures should be taken for early screening and prevention of renal tumors.

参考文献/References:

[1]Fiore DC, Fox CL. Urology and nephrology update: bladder and kidney cancer. Fp Essentials, 2014,416(1):26-29.
[2]Cheng P, Guan Y, Li H, et al. Urologic cancer in China. Jpn J Clin Oncol,2016,46(6):497-501.
[3]Siegel RL, Miller KD, Fedewa SA, et al. Colorectal cancer statistics, 2017. CA Cancer J Clin，2017,67(3):7-30.
[4]Fuhrman SA, Lasky LC, Limas C. Prognostic significance of morphologic parameters in renal cell carcinoma. Am J Surg Pathol,1982,6(7):655-663.
[5]Edge SB, Byrd DR, Compton CC, et al. AJCC cancer staging manual. 7th ed. New York: Springer, 2010.3-15.
[6]Corcoran AT, Russo P, Lowrance WT, et al. A review of contemporary data on surgically resected renal massesbenign or malignant? Urology,2013,81(4):707-713.
[7]Xiong YH, Zhang ZL, Li YH, et al. Benign pathological findings in 303 Chinese patients undergoing surgery for presumed localized renal cell carcinoma. Int J Urol,2010, 17(6):517-521.
[8]高玉堂,卢伟.上海市区恶性肿瘤发病率、死亡率和生存率(1973-2000).上海:上海第二军医大学出版社,2007.
[9]张宇,邵强,郭宇文,等.单中心8年泌尿男生殖系肿瘤检出情况及特征.临床和实验医学杂志,2016,15(19):1953-1956.
[10]Thompson RH, Kurta JM, Kaag M, et al. Tumor size is associated with malignant potential in renal cell carcinoma cases. J Urol,2009,181(5):2033-2036.
[11]Capitanio U, Montorsi F. Renal cancer.Lancet,2016,387(10021):894-906.
[12]Snyder ME, Bach A, Kattan MW, et al. Incidence of benign lesions for clinically localized renal masses smaller than 7 cm in radiological diameter: influence of sex. J Urol,2006,176(6):2391-2396.
[13]张永贞,杨国庆,张思维,等.中国2009年肾及泌尿系统其他癌发病和死亡分析.中国肿瘤,2013,22(5):333-337.
[14]李鸣,何志嵩,高江平,等.多中心肾癌临床特征分析.中华泌尿外科杂志,2010,31(2):77-80.
[15]Bauman TM, Potretzke AM, Wright AJ, et al. Partial Nephrectomy for presumed renalcell carcinoma: incidence, predictors, and perioperative outcomes of benign lesions.J Endourol，2017,31(4):412-417.
[16]Fujii Y, Komai Y, Saito K, et al. Incidence of benign pathologic lesions at partial nephrectomy for presumed RCC renal masses: Japanese dualcenter experience with 176 consecutive patients. Urology,2008,72 (3):598-602.
[17]包海龙, 陈鑫, 安云霞,等.单一机构414例肾血管平滑肌脂肪瘤临床病理特征.中华病理学杂志,2017,46(6):378-382.
[18]刘佳,林建,韩文科,等.肾嗜酸细胞瘤26例临床特征分析.中华外科杂志,2012,50(7):429-430.
[19]李汉忠,孙颖浩,魏强,等.中国18家医院2008~2012年肾癌诊治现状分析.中华泌尿外科杂志,2014,35(6):406-409.
[20]Kim SP, Thompson RH, Boorjian SA, et al. Comparative effectiveness for survival and renal function of partial and radical nephrectomy for localized renal tumors: a systematic review and metaanalysis. J Urol,2012,188(1):51-57.
[21]刘佳毅,王志向,刘冰,等.乳头状肾细胞癌临床特征及预后相关因素分析(附113例报告).第二军医大学学报,2016,37(8):1049-1052.
[22]王志华,杜立环,胡志全,等.肾嫌色细胞癌临床特征分析.中华外科杂志,2011,49(4):320-323.

备注/Memo

备注/Memo:
*通讯作者，E-mail：malulin@medmail.com.cn①北京市海淀医院（北京大学第三医院海淀院区）泌尿外科，北京100080②（北京大学第三医院病理科，北京100191）
更新日期/Last Update: 2018-09-04