[1]姜秀峰  周晓平  胡小吾  王来兴  徐波涛  刘建民  王文仲.帕金森病立体定向手术颅内出血并发症的原因分析[J].中国微创外科杂志,2003,03(5):427-428.
 Jiang Xiufeng,Zhou Xiaoping,HuXiaowu,et al.Hemorrhagic complications after sterotactic surgery for Parkinson's disease: An etiologic analysis[J].Chinese Journal of Minimally Invasive Surgery,2003,03(5):427-428.
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帕金森病立体定向手术颅内出血并发症的原因分析()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
03
期数:
2003年5期
页码:
427-428
栏目:
短篇论著
出版日期:
2003-05-31

文章信息/Info

Title:
Hemorrhagic complications after sterotactic surgery for Parkinson's disease: An etiologic analysis
作者:
姜秀峰  周晓平  胡小吾  王来兴  徐波涛  刘建民  王文仲
第二军医大学长海医院神经外科,上海,200433
Author(s):
Jiang XiufengZhou Xiaoping HuXiaowuet al.
Department ofNeurosurgery,ChanghaiHospital ofSecondMilitaryMedical University,Shanghai200433,China
关键词:
帕金森病立体定向出血并发症
Keywords:
Parkinson’s disease Sterotactic Hemorrhage Complication
分类号:
R742.5
文献标志码:
A
摘要:
目的探讨帕金森病立体定向手术颅内出血并发症的原因及对策. 方法 1999年4月~2001年12月我们对药物治疗效果不理想的350例帕金森病行立体定向毁损手术,术后6例出现颅内出血,其中毁损灶出血3例,穿刺道出血3例. 结果手术治疗4例,保守治疗2例.术后意识恢复但遗留偏瘫4例;非手术治疗2例,恢复良好,未遗留明显功能障碍.全组无死亡病例. 结论颅内出血并发症与微电极反复穿刺、毁损温度过高、手术操作精细度、患者全身情况等因素有关.采用磁共振结合微电极导向提高靶点定位精确度,减少微电极记录针道数,降低毁损温度,重视手术操作,注意患者全身情况,加强围手术期处理等措施,有助于降低颅内出血并发症的危险.
Abstract:
Objective To discuss the causes and the management of hemorrhagic complications after sterotactic surgery for Parkinson’ s disease (PD). Methods Atotal of 350 PD patients unresponsive to drug therapy fromApril 1999 to December 2001 underwent sterotactic surgery. Intracranial hemorrhage occurred in 6 cases, consisting of 3 cases of lesion hemorrhage and 3 cases of puncture path hemorrhage.  Results Of the 6 cases, 4 were treated by surgical operations, with recovery of consciousness but hemiplegia left, and 2 were treated conser- vatively without dysfunction left. No fatal cases were seen in the study. Conclusions Hemorrhagic complications are often in association with repeated puncture, excessive heat, operative skills, patient’s general condition and so on. Accurate target location byMRI combinedwith microelectrode guidance, reduce of microelectrode recording times, lowering of the lesion temperature, and sufficient perioperative care cont- ribute to the prevention of intracranial hemorrhagic complications.

参考文献/References:

[1]Favre J,Burchiel KJ,Taha JM,et al.Outcome of unilateral and bilateral pallidotomy for Parkinson's disease:patient assessment. Neurosurgery,2000,46:344-353.
[2]周晓平,胡小吾,王来兴,等.微电极导向立体定向手术治疗帕金森病.第二军医大学学报,2001,22:752-754.
[3]隋邦森主编.脑血管疾病(MR、CT、DSA与临床).北京:人民卫生出版社,1991.86.
[4]Holtzheimer PE,Roberts DW,Darcey TW.Magnetic resonance imaging versus computed tomography for target localization in functional stereotactic neurosurgery. Neurosurgery,1999,45:290-297.
[5]胡小吾,周晓平,王来兴,等.苍白球腹后部毁损术中的靶点定位方法探讨.第二军医大学学报,2001,22:755-757.
[6]王来兴,周晓平,胡小吾,等.磁共振定位结合微电极记录技术手术治疗帕金森病.功能性和立体定向神经外科杂志,2000,13:137-139.
[7]Eskandar EN,Shinobu LA,Penney JB,et al.Stereotactic pallidotomy performed without using microelectrode guidance in patients with Parkinson's disease:surgical technique and 2-years results.J Neurosurg,2000,92:375-383.
[8]Vitek JL,Bakay RA,Hashimoto T,et al.Microelectrode-guided pallidotomy:technical approach and its application in medically intractable Parkinson's disease.J Neurosurg,1998,88:1027-1043.

更新日期/Last Update: 2014-07-02