[1]柴鑫贾帅军王瑞国曾玉红①姜超张晓勃李志琳②周江军③宋恩④许正伟**张正平**.关节镜辅助单孔脊柱手术与后路切开手术治疗退行性腰椎滑脱症的比较[J].中国微创外科杂志,2026,01(6):348-355.
 Chai Xin,Jia Shuaijun,Wang Ruiguo,et al.Comparison Between Arthroscopicassisted Uniportal Spinal Surgery and Posterior Lumbar Interbody Fusion for Degenerative Lumbar Spondylolisthesis[J].Chinese Journal of Minimally Invasive Surgery,2026,01(6):348-355.
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关节镜辅助单孔脊柱手术与后路切开手术治疗退行性腰椎滑脱症的比较()

《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
01
期数:
2026年6期
页码:
348-355
栏目:
临床研究
出版日期:
2026-06-22

文章信息/Info

Title:
Comparison Between Arthroscopicassisted Uniportal Spinal Surgery and Posterior Lumbar Interbody Fusion for Degenerative Lumbar Spondylolisthesis
作者:
柴鑫贾帅军王瑞国曾玉红①姜超张晓勃李志琳②周江军③宋恩④许正伟**张正平**
(西安市红会医院脊柱外科,西安710054)
Author(s):
Chai Xin Jia Shuaijun Wang Ruiguo et al.
Department of Spine Surgery, Xi’an Honghui Hospital, Xi’an 710054, China
关键词:
关节镜辅助单孔脊柱手术后路腰椎椎间融合术腰椎滑脱
Keywords:
Arthroscopicassisted uniportal spinal surgeryPosterior lumbar interbody fusionLumbar spondylolisthesis
文献标志码:
A
摘要:
目的探讨关节镜辅助单孔脊柱手术(arthroscopicassisted uniportal spinal surgery,AUSS)与后路腰椎椎间融合术(posterior lumbar interbody fusion,PLIF)治疗退行性腰椎滑脱症(degenerative lumbar spondylolisthesis,DLS)的疗效。方法回顾2023年10月~2024年12月54例DLS资料,其中24例采用AUSS减压椎间植骨融合联合经皮椎弓根钉固定(AUSS组),30例采用后路切开减压复位椎间植骨融合(PLIF组)。2组一般资料差异无显著性(P>0.05)。比较2组手术时间、术中出血量、术后引流量、住院时间及并发症;术前及术后2周、1个月、3个月、6个月疼痛视觉模拟评分(Visual Analogue Scale,VAS)、Oswestry功能障碍指数(Oswestry Disability Index,ODI)。末次随访采用Bridwell法评估椎间融合情况,采用改良MacNab标准评估疗效。结果与PLIF组相比,AUSS组手术时间较长[(252.8±41.3)min vs. (129.3±10.0)min,P=0.000],但术中出血量[(128.0±21.5)ml vs. (172.9±26.7)ml]、术后引流量[(104.5±16.7)ml vs. (162.6±22.2)ml]、住院时间[(8.4±1.6)d vs. (11.0±1.6)d]均明显减少(均P=0.000)。AUSS组无并发症发生,PLIF组硬膜囊撕裂3例、一过性L5神经根麻痹1例。2组随访时间6~12个月[(9.8±2.5)月]。2组术后各时点疼痛VAS评分、ODI均较术前明显改善(P<005),AUSS组术后2周[(2.6±0.7)分vs.(3.8±0.7)分]、1个月[(1.8±0.4)分vs.(3.2±0.5)分]、3个月[(1.3±0.6)分vs.(2.0±0.2)分]VAS评分低于PLIF组(均P=0.000),术后2周[(24.8±2.5)% vs.(35.7±2.5)%]、1个月[(22.2±2.3)% vs.(31.2±2.7)%]、3个月[(16.7±1.8)% vs.(23.3±1.9)%]、6个月[(10.8±1.4)% vs.(15.4±1.5)%]ODI均低于PLIF组(均P=0.000)。末次随访2组均为BridwellⅠ级、Ⅱ级融合,2组椎间融合情况、改良MacNab疗效评价和滑脱复位率[(92.8±2.3)% vs. (91.8±3.3)%]差异均无显著性(均P>0.05)。结论与经典的PLIF相比,AUSS治疗DLS虽然手术时间较长,但出血少,恢复快,并发症少,且疗效相同。
Abstract:
ObjectiveTo compare the clinical efficacy of arthroscopicassisted uniportal spinal surgery (AUSS) and posterior lumbar interbody fusion (PLIF) in the treatment of degenerative lumbar spondylolisthesis (DLS).MethodsClinical data of 54 cases of DLS from October 2023 to December 2024 were retrospectively analyzed, including 24 patients undergoing AUSS for decompression, interbody bone graft fusion, and percutaneous pedicle screw fixation (AUSS group), and 30 patients undergoing posterior open decompression, reduction, and interbody bone graft fusion (PLIF group). There was no significant difference in the general data between the two groups (P>0.05), and the two groups were compared regarding operative time, intraoperative blood loss, postoperative drainage volume, hospital stay, and complications. The pain Visual Analogue Scale (VAS) scores and Oswestry Disability Index (ODI) were assessed preoperatively and at 2 weeks, 1 month, 3 months, and 6 months postoperatively. At the final followup, interbody fusion was evaluated by the Bridwell grading system, and clinical outcomes were assessed by using the modified MacNab criteria.ResultsCompared to the PLIF group, the AUSS group had a longer operative time [(252.8±41.3) min vs. (129.3±10.0) min, P=0.000], less intraoperative blood loss [(128.0±21.5) ml vs. (172.9±26.7) ml, P=0.000], less postoperative drainage [(104.5±16.7) ml vs. (162.6±22.2) ml, P=0.000], and shorter postoperative hospital stay [(8.4±16) d vs. (11.0±1.6) d, P=0.000]. No complications occurred in the AUSS group, while the PLIF group experienced 3 cases of dural sac tear and 1 case of transient L5 nerve root paralysis. The followup period for both groups ranged from 6 to 12 months [mean, (9.8±2.5) months]. The VAS scores and ODI at all postoperative time points were significantly improved compared to preoperative values in both groups (P<0.05). The AUSS group had significantly lower VAS scores at 2 weeks [(2.6±0.7) vs. (3.8±0.7)], 1 month [(1.8±0.4) vs. (3.2±0.5)], and 3 months postoperatively [(1.3±0.6) vs. (2.0±0.2)] (all P=0.000) and significantly lower ODI at 2 weeks [(24.8±2.5)% vs. (35.7±2.5)%], 1 month [(222±2.3)% vs. (31.2±2.7)%], 3 months [(16.7±1.8)% vs. (23.3±1.9)%], and 6 months postoperatively [(10.8±1.4)% vs. (15.4±1.5)%] compared to the PLIF group (all P=0.000). At the final followup, all the patients in both groups achieved Bridwell grade Ⅰ or Ⅱ fusion. No statistically significant differences were found between the two groups in terms of interbody fusion grade, modified MacNab criteria outcome, or spondylolisthesis reduction rate [(92.8±2.3)% vs. (91.8±3.3)%] (all P>005).Conclusion Compared with conventional PLIF, the treatment of DLS with AUSS, although requiring a longer operative time, results in less blood loss, faster recovery, and fewer complications, while achieving comparable clinical efficacy.

参考文献/References:

[1]赵志刚,刘晓光.微创经椎间孔入路腰椎椎间融合术治疗腰椎退行性疾病的研究进展.中国脊柱脊髓杂志,2019,29(4):371-375.
[2]Cho JH,Lee JH,Song KS,et al.Treatment outcomes for patients with failed back surgery.Pain Physician,2017,20(1):E29-E43.
[3]Li Y,Qian F,Sun F,et al.Arthroscopicassisted uniportal spinal surgery combined with modified unilateral laminotomy with bilateral decompression for the treatment of lumber epidural lipomatosis:case report and new therapeutic method.J Orthop,2024,58:90-95.
[4]Chen HW,Wang ZQ,Jing PJ,et al.Arthroscopicassisted uniportal spinal surgery for treatment of lumbar burst fractures complicated with neurological symptoms:a case report.J Int Med Res,2025,53(1):645593540.
[5]Wang F,Wang R,Zhang C,et al.Clinical effects of arthroscopicassisted uniportal spinal surgery and unilateral biportal endoscopy on unilateral laminotomy for bilateral decompression in patients with lumbar spinal stenosis:a retrospective cohort study.J Orthop Surg Res,2024,19(1):167.
[6]Liu Z,Hao S,Li X,et al.Clinical efficacy of AUSS/UNSESTLIF in the treatment of singlesegment degenerative lumbar spinal stenosis:a retrospective study.J Orthop Surg Res,2025,20(1):352.
[7]金翼飞,钱智恒,杨宗衡,等.颈腰综合征患者一期行颈椎减压术后腰椎症状改善的影像学预测因素分析.中国脊柱脊髓杂志,2025,35(6):568-578.
[8]陈豪杰,徐亮,周海城,等.弥漫性特发性骨质增生症伴腰椎管狭窄症的影像学特征.中国脊柱脊髓杂志,2023,33(8):697-706.
[9]尹鹏,海涌,杨晋才,等.经皮内镜下经椎间孔与传统后入路椎间融合术治疗伴有腰椎不稳的腰椎管狭窄症的疗效对比.中国脊柱脊髓杂志,2021,31(3):213-221.
[10]Marchi L,Abdala N,Oliveira L,et al.Radiographic and clinical evaluation of cage subsidence after standalone lateral interbody fusion.J Neurosurg Spine,2013,19(1):110-118.
[11]杨康,彭帅,常磊,等.单侧双通道内镜腰椎融合术与微创经椎间孔入路腰椎融合术治疗单节段腰椎退行性疾病对比观察.山东医药,2023,63(8):71-74.
[12]孙凤龙,梁庆晨,王宏庆,等.脊柱内镜下经椎间孔腰椎椎间融合术治疗腰椎间盘突出症伴腰椎不稳的早期临床研究.中华骨与关节外科杂志,2019,12(10):754-760.
[13]段琪飞,黄帅豪,梁国彦,等.两种经椎间孔减压椎间融合术治疗腰椎退行性疾病的疗效及多裂肌损伤对比.中国脊柱脊髓杂志,2023,33(1):27-36.
[14]He BL,Zhu ZC,Lin LQ,et al.Comparison of biportal endoscopic technique and uniportal endoscopic technique in Unilateral Laminectomy for Bilateral Decomprssion (ULBD) for lumbar spinal stenosis.Asian J Surg,2024,47(1):112-117.
[15]Stein IC,Than KD,Chen KS,et al.Failure of a polyetheretherketone expandable interbody cage following transforaminal lumbar interbody fusion.Eur Spine J,2015,24 Suppl 4:S555-S559.
[16]肖清清,李越,楚福明,等.双操作通道全内镜下远外侧经椎间孔入路腰椎椎间融合术治疗腰椎滑脱症的临床疗效.中国脊柱脊髓杂志,2025,35(7):715-721.
[17]刘仲宇,董健文,陈子豪,等.单节段镜下融合治疗合并骨质疏松症的腰椎退变性疾病的近期疗效.中国脊柱脊髓杂志,2024,34(8):834-842.
[18]刘俊麟,余强,冯品,等.手术区域全密闭技术在经皮同轴大通道内镜下腰椎融合术治疗退行性腰椎滑脱症中的应用.中国脊柱脊髓杂志,2024,34(6):576-584.
[19]杨进,孔清泉,吴浩,等.重度腰椎滑脱手术的L5神经根牵张损伤机制.中国矫形外科杂志,2021,29(17):1573-1578.
[20]朱剑,镐英杰,任志楠,等.单侧双通道内镜下腰椎融合术治疗腰椎退行性疾病的初步研究.中国脊柱脊髓杂志,2021,31(11):1026-1033.
[21]卢乾威,沈茂,徐子航,等.单通道与单侧双通道脊柱内镜下腰椎间融合术治疗单节段腰椎退行性疾病的早期疗效及学习曲线.中国脊柱脊髓杂志,2023,33(6):489-496,504.
[22]White CA,Patel AV,Butler LR,et al.Comparison of patient preference,understanding,and sentiment for minimally invasive versus open spine surgery.Spine (Phila Pa 1976),2022,47(4):309-316.
[23]Fukushima M,Ohtomo N,Noma M,et al.Microendoscopeassisted versus open posterior lumbar interbody fusion for lumbar degenerative disease:a multicenter retrospective cohort study.Medicina (Kaunas),2021,57(2):150.
[24]Mooney J,Michalopoulos GD,Alvi MA,et al.Minimally invasive versus open lumbar spinal fusion:a matched study investigating patientreported and surgical outcomes.J Neurosurg Spine,2022,36(5):753-766.

备注/Memo

备注/Memo:
基金项目:陕西省自然科学基础研究计划(2023-JC-YB-814)**通讯作者,Email:wzzppzz@qq.com(张正平);irenewayne@126.com(许正伟)①(西安市红会医院骨质疏松科,西安710054)②(四川省广元市中心医院骨科,广元628000)③(中国人民解放军联勤保障部队第九〇八医院骨科,南昌330000)④(昆明医科大学第一附属医院运动医学科,昆明650021)
更新日期/Last Update: 2026-06-22