[1]胥子玮 王庆源 封益飞 王勇 黄远健 张冬生 张川 傅赞 孙跃明**.腹腔镜辅助全结直肠切除、回肠J型储袋与肛管吻合治疗家族性腺瘤性息肉病[J].中国微创外科杂志,2018,18(11):1034-1036.
 Xu Ziwei,Wang Qingyuan,Feng Yifei,et al.Laparoscopic Assisted Total Colorectal Resection and Ileal Jpouch Anal Anastomosis in the Treatment of Familial Adenomatous Polyposis[J].Chinese Journal of Minimally Invasive Surgery,2018,18(11):1034-1036.
点击复制

腹腔镜辅助全结直肠切除、回肠J型储袋与肛管吻合治疗家族性腺瘤性息肉病()
分享到:

《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
18
期数:
2018年11期
页码:
1034-1036
栏目:
经验交流
出版日期:
2018-11-20

文章信息/Info

Title:
Laparoscopic Assisted Total Colorectal Resection and Ileal Jpouch Anal Anastomosis in the Treatment of Familial Adenomatous Polyposis
作者:
胥子玮 王庆源 封益飞 王勇 黄远健 张冬生 张川 傅赞 孙跃明**
(南京医科大学第一附属医院结直肠外科,南京210002)
Author(s):
Xu Ziwei Wang Qingyuan Feng Yifei et al.
Department of Colorectal Surgery, First Affiliated Hospital of Nanjing Medical University, Nanjing 210002, China
关键词:
全结直肠切除腹腔镜家族性腺瘤性息肉病回肠J型储袋
Keywords:
Total colorectal resectionLaparoscopyFamilial adenomatous polyposisIleal Jpouch
文献标志码:
B
摘要:
目的探讨腹腔镜辅助全结直肠切除、回肠J型储袋与肛管吻合治疗家族性腺瘤性息肉病(familial adenomatous polyposis,FAP)的疗效。方法2013年1月~2017年12月对15例FAP施行全结直肠切除、回肠J型储袋与肛管吻合术。先行腔镜下全结直肠的游离,离断直肠,然后将回肠断端构建J形储袋,经肛门放置直线管状吻合器,拉下回肠,完成贮袋肛管吻合。结果15例均顺利完成腹腔镜辅助下全结直肠切除术、回肠J型储袋与肛管吻合。手术时间(112.4±323)min,术后住院时间(9.9±2.5)d。术后病理4例息肉恶变。术后1例出现盆腔感染,穿刺引流后好转。15例平均随访28个月(3~60个月),术后随访1年时,大便次数(3.3±1.4)次/d,基本成形,无肿瘤复发及死亡。结论腹腔镜辅助全结直肠切除、回肠J型储袋与肛管吻合是治疗FAP的有效手术方式。
Abstract:
ObjectiveTo investigate the efficacy of laparoscopic assisted total colorectal resection and ileal Jpouch anal anastomosis in the treatment of familial adenomatous polyposis (FAP).MethodsThe clinical and followup data of 15 patients with FAP who underwent total colorectal resection and ileal Jpouch anal anastomosis in our hospital from January 2013 to December 2017 were analyzed retrospectively. During the operation, total colorectal dissection was performed by using laparoscopy. Then the Jshaped storage bag was constructed at the end of the ileum, and a straight tubular anastomosis device was placed through the anus to complete pouch anal anastomosis.ResultsAll the 15 patients received successful laparoscopic assisted total colorectal resection and ileal Jpouch anal anastomosis. The operation time was (1124±323) min, and the postoperative hospital stay was (9.9±2.5) d. Pathological results showed 4 cases of malignant lesions. Postoperative pelvic infection occurred in 1 case, which was relieved after puncture and drainage. The average followup time was 28 months (range, 3-60 months). After one year of followup, the average number of stools was (3.3±1.4) times/d, which were basically formed. No recurrence or death was seen.ConclusionLaparoscopic assisted total colorectal resection and ileal Jpouch anal anastomosis is an effective treatment for FAP.

参考文献/References:

[1]Kerr SE, Thomas CB, Thibodeau SN, et al. APC germline mutations in individuals being evaluated for familial adenomatous polyposis: a review of the Mayo Clinic experience with 1591 consecutive tests. J Mol Diagn,2013,15(1):31-43.
[2]Vasen HF, Moslein G, Alonso A, et al. Guidelines for the clinical management of familial adenomatous polyposis (FAP). Gut,2008,57(5):704-713.
[3]中国抗癌协会大肠癌专业委员会遗传学组.遗传性结直肠癌临床诊治和家系管理.中华肿瘤杂志,2018,40(1):64-77.
[4]Aihara H, Kumar N, Thompson CC. Diagnosis, surveillance, and treatment strategies for familial adenomatous polyposis: rationale and update. Eur J Gastroenterol Hepatol,2014,26(3):255-262.
[5]Kastrinos F, Syngal S. Inherited colorectal cancer syndromes. Cancer J,2011,17(6):405-415.
[6]丁召,吴云华,秦前波,等.回肠D型储袋在溃疡性结肠炎和家族性腺瘤性息肉病手术治疗中的应用.中华胃肠外科杂志,2015,18(12):1231-1234.
[7]Noh GT, Han J, Cho MS, et al. Factors affecting pouchrelated outcomes after restorative proctocolectomy. PLoS One,2017,12(10):e0186596.
[8]张昭,王丹,徐彬,等.腹腔镜辅助全结直肠切除术治疗家族性腺瘤性息肉病.中华普通外科杂志,2015,30(9):711-714.
[9]耿岩,胡彦锋,余江,等.中间入路法腹腔镜辅助全结直肠切除的临床应用.中华胃肠外科杂志,2013,16(1):32-35.
[10]吴凯,喻春钊.低位直肠癌及其腹腔镜手术特殊性与预防性造口的选择.中国微创外科杂志,2017,17(9):832-835.

备注/Memo

备注/Memo:
*基金项目:国家自然科学基金(81400835)**通讯作者,Email:njmusunyueming@163.com
更新日期/Last Update: 2019-03-01