[1]徐康,王建坤①,于泓**①,等.内镜下球囊扩张联合博来霉素注射在难治性直肠术后吻合口良性狭窄中的应用[J].中国微创外科杂志,2018,18(7):657-660.
 Xu Kang*,Wang Jiankun,Yu Hong,et al.Endoscopic Dilation Combined With Injection of Bleomycin for Refractory Anastomotic Benign Stricture After Rectal Surgery[J].Chinese Journal of Minimally Invasive Surgery,2018,18(7):657-660.
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内镜下球囊扩张联合博来霉素注射在难治性直肠术后吻合口良性狭窄中的应用()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
18
期数:
2018年7期
页码:
657-660
栏目:
新技术新方法
出版日期:
2018-10-11

文章信息/Info

Title:
Endoscopic Dilation Combined With Injection of Bleomycin for Refractory Anastomotic Benign Stricture After Rectal Surgery
作者:
徐康王建坤①于泓**①赵黎黎①王翔①缪林②
江苏省东台市人民医院消化内科,东台224200
Author(s):
Xu Kang* Wang Jiankun Yu Hong et al.
*Department of Gastroenterology, Dongtai People’s Hospital, Dongtai 224200, China
Keywords:
Rectal surgeryAnastomotic strictureEndoscopic dilationBleomycin
文献标志码:
B
Abstract:
ObjectiveTo investigate the efficacy and safety of endoscopic dilation combined with injection of bleomycin for refractory anastomotic benign stricture after rectal surgery.MethodsClinical data of 16 patients with refractory anastomotic benign stricture after rectal surgery who received endoscopic dilation or combined with injection of bleomycin were retrospectively analyzed, including 9 cases of dilation with bleomycin injection (bleomycin group) and 7 cases of simple dilation (dilation group). The clinical efficacy and adverse events were compared between the two groups.Results All the patients received endoscopic treatment with a 100% success rate. The strictures were managed successfully and the obstruction symptoms were relieved. Minor complication occurred in 1 case in the bleomycin group and no complication occurred in the dilation group. The two groups had no significant difference in the complication rate (Fisher’s Exact Test, P=1.000). The mean re-intervention interval was (8.0±1.5) months in the bleomycin group and (5.1±1.0) months in the dilation group. The difference between the two groups was significant (t=4.417, P=0.001).ConclusionCompared with endoscopic dilation, endoscopic dilation combined with bleomycin injection can prolong re-intervention interval, which is a safe and effective endoscopic management.

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金青年基金(81700577)**通讯作者,E-mail:fish0021@163.com ①(江苏省人民医院消化内镜中心,南京210029) ②(南京医科大学第二附属医院消化内科,南京210011)
更新日期/Last Update: 2018-10-11