参考文献/References:
[1]Chen W,Zheng R,Baade PD,et al.Cancer statistics in China,2015.CA Cancer J Clin,2016,66(2):115-132.
[2]Chang YR,Han DS,Kong SH,et al.The value of palliative gastrectomy in gastric cancer with distant metastasis.Ann Surg Oncol,2012,19(4):1231-1239.
[3]Wang YW,Zhu ML,Wang RF,et al.Predictable factors for lymph node metastasis in early gastric cancer analysis of clinicopathologic factors and biological markers.Tumour Biol,2016,37(7):8567-8578.
[4]Kimura K,Ojima H,Kubota D,et al.Proteomic identification of the macrophage-capping protein as a protein contributing to the malignant features of hepatocellular carcinoma.J Proteomics,2013,78:362-373.
[5]Morofuji N,Ojima H,Onaya H,et al.Macrophage-capping protein as a tissue biomarker for prediction of response to gemcitabine treatment and prognosis in cholangiocarcinoma.J Proteomics,2012,75(5):1577-1589.
[6]Ichikawa H,Kanda T,Kosugi S,et al.Laser microdissection and two-dimensional difference gel electrophoresis reveal the role of a novel macrophage-capping protein in lymph node metastasis in gastric cancer.J Proteome Res,2013,12(8):3780-3791.
[7]陈茉，丁士刚，刘琳娜，等.胃腺癌伴淋巴结转移的蛋白质组学分析.中国微创外科杂志，2012，12(4)：359-363.
[8]吕旻桦，梁博，徐康保，等.胃癌组织中CapG蛋白的表达及其与临床病理特征及预后的关系.临床与实验病理学杂志，2016，32(12)：1329-1333.
[9]Sun B,Hu C,Yang Z,et al.Midkine promotes hepatocellular carcinoma metastasis by elevating anoikis resistance of circulating tumor cells.Oncotarget,2017,8(20):32523-32535.
[10]Dawson H,Grundmann S,Koelzer VH,et al.Tyrosine kinase receptor B (TrkB) expression in colorectal cancers highlights anoikis resistance as a survival mechanism of tumour budding cells.Histopathology,2015,66(5):715-725.
[11]Okugawa Y,Tanaka K,Inoue Y,et al.Brain-derived neurotrophic factor/tropomyosin-related kinase B pathway in gastric cancer.Br J Cancer,2013,108(1):121-130.
[12]Tanaka K,Shimura T,Kitajima T,et al.Tropomyosin-related receptor kinase B at the invasive front and tumour cell dedifferentiation in gastric cancer.Br J Cancer,2014,110(12):2923-2934.
[13]Chen B,Liang Y,He Z,et al.Autocrine activity of BDNF induced by the STAT3 signaling pathway causes prolonged TrkB activation and promotes human non-small-cell lung cancer proliferation.Sci Rep,2016,6:30404.
[14]赵梅莘，丁士刚，刘琳娜，等.术前胃镜下胃黏膜活检组织TrkB、TRIM29表达对胃癌淋巴结转移的预测价值.中华医学杂志，2012，92(6)：376-379.
[15]Fujikawa H,Tanaka K,Toiyama Y,et al.High TrkB expression levels are associated with poor prognosis and EMT induction in colorectal cancer cells.J Gastroenterol,2012,47(7):775-784.
[16]Elsir T,Smits A,Lindstrom MS,et al.Transcription factor PROX1: its role in development and cancer.Cancer Metastasis Rev,2012,31(3-4):793-805.
[17]Park YL,Myung E,Park SY,et al.Impact of prospero homeobox-1 on tumor cell behavior and prognosis in colorectal cancer.Am J Cancer Res,2015,5(11):3286-3300.
[18]魏军成，罗丹枫，马丁.乳腺癌组织中LYVE-1和PROX-1的表达及临床意义.华中科技大学学报（医学版），2014,43(4)：431-433,440.
[19]Taban O,Cimpean AM,Raica M,et al.PROX1 expression in gastric cancer: from hypothesis to evidence.Anticancer Res,2014,34(7):3439-3446.
[20]Park KJ,Cho SB,Park YL,et al.Prospero homeobox 1 mediates the progression of gastric cancer by inducing tumor cell proliferation and lymphangiogenesis.Gastric Cancer,2017,20(1):104-115.
[21]Shao C,Duan C,Wang J,et al.Expression of microtubule-associated protein TPX2 in human gastric carcinoma and its prognostic significance.Cancer Cell Int,2016,16:79.
[22]Wei P,Zhang N,Xu Y,et al.TPX2 is a novel prognostic marker for the growth and metastasis of colon cancer.J Transl Med,2013,11:313.
[23]Liu Q,Yang P,Tu K,et al.TPX2 knockdown suppressed hepatocellular carcinoma cell invasion via inactivating AKT signaling and inhibiting MMP2 and MMP9 expression.Chin J Cancer Res,2014,26(4):410-417.
[24]Miwa T,Kokuryo T,Yokoyama Y,et al.Therapeutic potential of targeting protein for Xklp2 silencing for pancreatic cancer.Cancer Med,2015,4(7):1091-1100.
[25]Zorba A,Buosi V,Kutter S,et al.Molecular mechanism of Aurora A kinase autophosphorylation and its allosteric activation by TPX2.Elife,2014,3:e2667.
[26]Liang B,Zheng W,Fang L,et al.Overexpressed targeting protein for Xklp2 (TPX2) serves as a promising prognostic marker and therapeutic target for gastric cancer.Cancer Biol Ther,2016,17(8):824-832.
[27]Tomii C,Inokuchi M,Takagi Y,et al.TPX2 expression is associated with poor survival in gastric cancer.World J Surg Oncol,2017,15(1):14.
[28]Zhao W,Zhu H,Zhang S,et al.Trop2 is overexpressed in gastric cancer and predicts poor prognosis.Oncotarget,2016,7(5):6136-6145.
[29]Zhao W,Ding G,Wen J,et al.Correlation between Trop2 and amphiregulin coexpression and overall survival in gastric cancer.Cancer Med,2017，6（5）：994-1001.
[30]Shabestarian H,Ghodsi M,Mallak AJ,et al.DPPA2 protein expression is associated with gastric cancer metastasis.Asian Pac J Cancer Prev,2015,16(18):8461-8465.