[1]李伟,张文涛,江长青,等.肩峰下镇痛泵联合氟比洛芬酯用于肩关节镜术后镇痛的随机对照研究[J].中国微创外科杂志,2017,17(08):691-697.
　Li Wei,Zhang Wentao,Jiang Changqing,et al.Subacromial Patientcontrolled Anesthetics with Intravenous Flurbiprofen Axetil for Postoperative Analgesia of Arthroscopic Shoulder Surgery: a Randomized Controlled Trial[J].Chinese Journal of Minimally Invasive Surgery,2017,17(08):691-697.
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肩峰下镇痛泵联合氟比洛芬酯用于肩关节镜术后镇痛的随机对照研究()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
17
期数:
2017年08期
页码:
691-697
栏目:
临床论著
出版日期:
2017-08-20

文章信息/Info

Title:
Subacromial Patientcontrolled Anesthetics with Intravenous Flurbiprofen Axetil for Postoperative Analgesia of Arthroscopic Shoulder Surgery: a Randomized Controlled Trial
作者:
李伟; 张文涛; 江长青; 陈鹏; 李九群; 任时香; 伍晓*
北京大学深圳医院运动医学科，深圳518036
Author(s):
Li Wei;  Zhang Wentao;  Jiang Changqing;  et al.
Department of Sports Medicine, Peking University Shenzhen Hospital, Shenzhen 518036, China
关键词:
肩峰下; 自控镇痛; 氟比洛芬酯; 肩关节镜手术; 术后镇痛
Keywords:
Subacromial; Patientcontrolled analgesia; Flurbiprofen axetil; Arthroscopic shoulder surgery; Postoperative analgesia
文献标志码:
A
摘要:
目的评价肩峰下置罗哌卡因镇痛泵联合静脉注射氟比洛芬酯用于肩关节镜术后康复镇痛效果。方法2013年4月~2015年9月105例肩关节镜术后随机分为3组进行镇痛，分别为肩峰下置镇痛泵镇痛组（S组），罗哌卡因150 mg肩峰下置自控镇痛泵；氟比洛芬酯组（I组），静脉给予氟比洛芬酯100 mg；肩峰下置镇痛泵联合静脉氟比洛芬酯注射镇痛组（S+I组），联合前二者用药，术后进行康复锻炼。观察患者不良反应发生及切口情况，进行术后8 h和1、3、14 d疼痛数字分级法（numeric pain intensity scale,NPIS)评分和肩关节功能评分(American shoulder and elbow surgeons scale, ASES)。结果3组术后8 h和1、3、14 d NPIS评分有显著性差异（P=0.000），其中 S+I组明显低于S组和I组（P<005），S组明显低于I组（P<0.05）。3组间术后8 h、1 d、3 d、14 d ASES评分有显著性差异（P=0.000），其中S+I组明显优于S组和I组（P<005），S组优于I组（P<0.05）。3组不良反应为恶心、呕吐，发生率为16.2%（17/105）），S组明显低于S+I组和I组（χ2=4.590，P=0.032； χ2=4.590，P=0.032)。术后2周随访患者肩关节切口无感染和红肿。结论肩峰下置罗哌卡因镇痛泵联合静脉注射氟比洛芬酯安全，肩外科手术后及早期康复锻炼镇痛效果好，无感染，不良反应发生率低。
Abstract:
ObjectiveTo evaluate the effect of subacromial patientcontrolled anesthetic pump with intravenous flurbiprofen axetil for postoperative analgesia of arthroscopic shoulder surgery. MethodsA total of 105 patients were randomly divided into 3 groups with 35 cases in each group: the subacromial patientcontrolled analgesic (S) group, the intravenous flurbiprofen axetil (I) group, and the subacromial patientcontrolled analgesic with intravenous flurbiprofen axetil (S+I) group. In the S group, the patients were treated with subacromial patientcontrolled anesthetics of 150 mg ropivacaine; in the I group, the patients were treated with intravenous 100 mg flurbiprofen axetil; in the S+I group, the patients were treated with subacromial patientcontrolled anesthetics of 150 mg ropivacaine and intravenous 100 mg flurbiprofen axetil. The pain was regularly assessed by numeric pain intensity scale (NPIS) and the function of shoulder was regularly assessed by American shoulder & elbow surgeon score (ASES) at 8 h, 1 day, 3 days, and 14 days. ResultsThe three groups had significant difference in the postoperative NPIS at 8 h, 1 day, 3 days, and 14 days after operation (P=0.000). The scores were lower in the S+I group than the I group and the S group (P<0.05), and lower in the S group than the I group (P<0.05). The three groups had significant difference in the postoperative ASES at 8 h, 1 day, 3 days, and 14 days (P=0.000). The scores were higher in the S+I group than the I group and the S group (P<0.05), and higher in the S group than the I group (P<0.05). The side effects included nausea and vomiting. The incidence was 16.2% (17/105). No infection or reddening welt was found.ConclusionThe subacromial patientcontrolled anesthetics of ropivacaine with intravenous flurbiprofen axetil has good analgesia effect and low incidence of side effects after arthroscopic shoulder surgery.

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备注/Memo

备注/Memo:
*通讯作者，Email：szwx_2016@126.com
更新日期/Last Update: 2017-11-22