[1]汪涛 李志民﹡ 陈文龙①.射频消融治疗甲状腺良性结节61例[J].中国微创外科杂志,2016,16(09):795-798.
 Wang Tao*,Li Zhimin*,Chen Wenlong..Radiofrequency Ablation for the Treatment of Thyroid Benign Nodules: a Report of 61 Cases[J].Chinese Journal of Minimally Invasive Surgery,2016,16(09):795-798.
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射频消融治疗甲状腺良性结节61例()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
16
期数:
2016年09期
页码:
795-798
栏目:
临床研究
出版日期:
2016-09-09

文章信息/Info

Title:
Radiofrequency Ablation for the Treatment of Thyroid Benign Nodules: a Report of 61 Cases
作者:
汪涛 李志民﹡ 陈文龙①
(厦门大学附属第一医院杏林分院普外科,厦门361022)
Author(s):
Wang Tao* Li Zhimin* Chen Wenlong.
*Department of General Surgery, Xinglin Branch of First Affiliated Hospital of Xiamen University, Xiamen 361022, China
关键词:
甲状腺良性结节超声引导射频消融移动消融
Keywords:
Thyroid benign noduleUltrasoundguidanceRadiofrequency ablationMoving shot technique
文献标志码:
A
摘要:
目的探讨超声引导下经皮射频消融治疗甲状腺良性结节的疗效。方法2013年2月~2014年5月对61例甲状腺良性结节( 87枚结节)超声引导下应用单针单极式射频消融针(18G×7 cm,射频工作段长度1 cm)进行消融治疗,观察术后1、3、6、12个月结节大小变化,测量结节最大径、体积、体积减少率。结果61例均成功完成射频消融,其中3例1个月后行二次消融。无一例严重并发症发生,2例穿刺部位血肿,1例声音嘶哑, 3例治疗中疼痛不适,1例呕吐,均顺利恢复。消融前结节最大径(2.24±0.63)cm,消融后1、3、6、12个月结节最大径分别为(1.82±0.81)、(1.52±0.72)、(1.03±0.43)、(0.56±0.36)cm;消融前结节体积(5.37±1.85)ml,消融后1、3、6、12个月结节体积分别为(4.41±2.16)、(3.19±1.92)、(134±0.61)、(0.69±0.41)ml;消融后体积减少率分别(20.7±13.2)%、(48.6±16.1)%、(77.3±4.7)%、(88.7±5.6)%。消融后第12个月,51个结节(58.6%)完全消失。结论超声引导下射频消融治疗甲状腺良性结节效果确切。
Abstract:
ObjectiveTo evaluate therapeutic effects of radiofrequency ablation for thyroid benign nodules.MethodsBy using the radiofrequency electrode (18G×7 cm, working segment length=1 cm), a total of 61 patients with 87 thyroid benign nodules underwent ultrasoundguided radiofrequency ablation in our department from February 2013 to May 2014. The maximum diameter, volume, and volumereduction ratio (VRR) were measured by ultrasound at 1, 3, 6, and 12 months after operation.ResultsThe 61 patients with 87 thyroid benign nodules were successfully treated with radiofrequency ablation, including 3 cases receiving secondary ablation after 1 month. The maximum diameter of thyroid nodules was (2.24±0.63) cm preoperatively, and (1.82±0.81) cm, (152±0.72) cm, (1.03±0.43) cm, and (0.56±0.36) cm at 1, 3, 6, and 12 months after ablation, respectively. The maximun volume was (5.37±1.85) ml preoperatively, and (4.41±2.16) ml, (3.19±1.92) ml, (1.34±061) ml, and (0.69±0.41) ml at 1, 3, 6, and 12 months after ablation, respectively. The VRR were (20.7±13.2)%, (48.6±16.1)%, (77.3±4.7)% and (88.7±5.6)%, respectively at 1,3,6, and 12 months after ablation. At the final followup, 51 (58.6%) nodules disappeared completely.ConclusionUltrasound guided radiofrequency ablation for thyroid benign nodules is safe and effective.

参考文献/References:

[1]Levine RA. Current guidelines for the management of thyroid nodules. Endocr Pract, 2012, 18(4):596-599.
[2]Rastogi A, Bhadada SK, Bhansali A. Nodular goiter with multiple cystic and solid swellings. Indian J Endocrinol Metabol, 2012,16(4):651-653.
[3]Goldberg SN.Radiofrequency tumor ablation: principles and techniques. Eur J Ultrasound,2001,13(2):129-147.
[4]Mcgahan JP, Gu WZ, Brock JM, et al. Hepatic ablation using biopolar radiofrequency electrocautery.Acad Radiol,1996,3 (5):418-422.
[5]刘文静,秦海峰.化疗联合射频消融毁损治疗晚期非小细胞肺癌的研究进展.中国微创外科杂志,2012,12(4):376-378.
[6]Choi D, Lim HK, Rhim H, et al. Percutaneous radiofrequency ablation for earlystage hepatocellular carcinoma as a firstline treatment: longterm results and prognostic factors in a large singleinstitution series. Eur Radiol,2007,17(3):684-692.
[7]Tan CT, Cheah WK, Delbridge L.“Scarless”(in the neck) endoscopic thyroidectomy(SET): an evidencebased review of published techniques. Word J Surg, 2008, 32(7):1349-1357.
[8]Dupuy DE, Monchik JM, Decrea C, et al. Radiofrequency ablation of regional recurrence from welldifferentiated thyroid malignancy. Surgery, 2001,130(6):971-977.
[9]Kim YS, Rhim H, Tae K, et al. Radiofrequency ablation of benign cold thyroid nodules: initial clinical experience. Thyroid, 2006, 16(4):361-367.
[10]Lee JH, Kim YS, Lee D, et al. Radiofrequency ablation(RFA)of benign thyroid nodules in patients with incompletely resolved clinical problems after ethanol ablation(EA). World J Surg, 2010,34(7):1488-1493.
[11]Spiezia S, Garberoglio R, Milone F, et al. Thyroid nodules and related symptoms are stably controlled two years after radiofrequency thermal ablation.Thyroid,2009,19(3):219-225.
[12]刘金涛,郭文斌,杨世财,等.超声引导下射频消融治疗结节性甲状腺肿46 例报告.中国微创外科杂志,2012,12(8):701-703.
[13]Baek JH, Lee JH, Sung JY, et al. Complications encountered in the treatment of benign thyroid nodules with USguided radiofrequency ablation: a multicenter study.Radiology,2012,262(1):335-342.
[14]Lim HK, Lee JH, Ha EJ, et al. Radiofrequency ablation of benign nonfunctioning thyroid nodules: 4year followup results for 111 patients. Eur Radiol,2013,23(4):1044-1049.
[15]Jeong WK, Baek JH, Rhim H, et al. Radiofrequency ablation of benign thyroid nodules: safety and imaging followup in 236 patients. Eur Radiol,2008,18(6):1244-1250.
[16]隋洋,吴凤林,胡洁,等.超声引导下射频消融甲状腺实性结节的临床应用价值.医学影像学杂志,2013,23(1):30-33.

备注/Memo

备注/Memo:
﹡通讯作者,Email:lizhimin@sina.com①超声科
更新日期/Last Update: 2016-12-09