[1]曲音音 综述 韩彬﹡ 审校.床旁即时检验在重症创伤患者围术期凝血功能监测中的应用[J].中国微创外科杂志,2016,16(06):558-561.
　Qu Yinyin,Han Bin..Research Progress of Perioperative Blood Coagulation Monitoring with Pointofcare Technique in Severe Trauma Patients[J].Chinese Journal of Minimally Invasive Surgery,2016,16(06):558-561.
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床旁即时检验在重症创伤患者围术期凝血功能监测中的应用()

《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
16
期数:
2016年06期
页码:
558-561
栏目:
文献综述
出版日期:
2016-09-08

文章信息/Info

Title:
Research Progress of Perioperative Blood Coagulation Monitoring with Pointofcare Technique in Severe Trauma Patients
作者:
曲音音 综述 韩彬﹡ 审校
（北京大学第三医院麻醉科，北京100083）
Author(s):
Qu Yinyin;  Han Bin.
Department of Anesthesiology, Peking University Third Hospital, Beijing 100083, China
关键词:
床旁即时检验; 血栓弹力图; 重症创伤; 凝血功能监测
Keywords:
Pointofcare technique; Thromboelastography; Severe trauma; Coagulation function monitoring
文献标志码:
A
摘要:
重症创伤患者往往伤情复杂，病情较重，可能引起大出血，大量输血可能导致凝血功能紊乱等并发症。床旁即时检验包括血小板功能和血栓弹力图检验，可以迅速地监测凝血功能动态变化，从而指导精确输注各种血制品，纠正凝血障碍，减少盲目大量输血和相关并发症。本文对床旁即时检验在重症创伤外科患者围术期的应用进展，及与传统凝血功能监测相比在早期诊断和减少死亡率等方面的优势进行文献综述。
Abstract:
Severe trauma patients are usually complicated to deal with. Massive hemorrhage or blood transfusion may lead to following coagulopathy. Pointofcare technique includes platelets function test and thromboelastography. The technique can provide rapid evaluation of blood coagulation status, and then deliver specific transfusion therapy in order to avoid excess transfusion and complications. We reviewed the research progress of perioperative blood coagulation monitoring with pointofcare technique in severe trauma patients, and compared it with traditional coagulation test.

参考文献/References:

[1]Brohi K, Singh J, Heron M, et al. Acute traumatic coagulopathy. J Trauma, 2003, 54(6):1127-1130.
[2]Cripps MW, Kutcher ME, Daley A, et al. Cause and timing of death in massively transfused trauma patients. J Trauma Acute Care Surg, 2013, 75(2 Suppl 2):S255-S262.
[3]霍雷, 张厚庆, 徐步靖, 等.经皮骶髂关节螺钉内固定治疗骨盆骨折.中国微创外科杂志,2013,13（4）:339-342.
[4]顾宇彤, 张键, 姜晓幸, 等.微创椎弓根钉对经皮椎体成形术后再骨折的预防作用.中国微创外科杂志,2014，14（10）: 869-874.
[5]Clevenger B and Mallett SV. Transfusion and coagulation management in liver transplantation. World J Gastroenterol, 2014, 20(20):6146-6158.
[6]Sarani B, Dunkman WJ, Dean L, et al. Transfusion of fresh frozen plasma in critically ill surgical patients is associated with an increased risk of infection. Crit Care Med, 2008, 36(4):1114-1118.
[7]Haas T, Spielmann N, Mauch J, et al. Comparison of thromboelastometry (ROTEM(R)) with standard plasmatic coagulation testing in paediatric surgery. Br J Anaesth, 2012, 108(1):36-41.
[8]Spalding GJ, Hartrumpf M, Sierig T, et al. Cost reduction of perioperative coagulation management in cardiac surgery: value of "bedside" thrombelastography (ROTEM). Eur J Cardiothorac Surg, 2007, 31(6):1052-1057.
[9]British Committee for Standards in Haematology, Stainsby D, MacLennan S, et al. Guidelines on the management of massive blood loss. Br J Haematol, 2006, 135(5):634-641.
[10]Watson GA, Sperry JL, Rosengart MR, et al. Fresh frozen plasma is independently associated with a higher risk of multiple organ failure and acute respiratory distress syndrome. J Trauma, 2009, 67(2):221-230.
[11]Tapia NM, Chang A, Norman M, et al. TEGguided resuscitation is superior to standardized MTP resuscitation in massively transfused penetrating trauma patients. J Trauma Acute Care Surg, 2013, 74(2):378-385.
[12]Gorlinger K, Fries D, Dirkmann D, et al. Reduction of fresh frozen plasma requirements by perioperative pointofcare coagulation management with early calculated goaldirected therapy. Transfus Med Hemother, 2012, 39(2):104-113.
[13]Enriquez LJ,ShoreLesserson L. Pointofcare coagulation testing and transfusion algorithms. Br J Anaesth, 2009, 103 (Suppl 1): i14-i22.
[14]Larsen OH, FengerEriksen C, Christiansen K, et al. Diagnostic performance and therapeutic consequence of thromboelastometry activated by kaolin versus a panel of specific reagents. Anesthesiology, 2011, 115(2):294-302.
[15]Maegele M, Lefering R, Yucel N, et al. Early coagulopathy in multiple injury: an analysis from the German Trauma Registry on 8724 patients. Injury, 2007, 38(3):298-304.
[16]Ostrowski SR, Srensen AM, Larsen CF, et al. Thrombelastography and biomarker profiles in acute coagulopathy of trauma: a prospective study. Scand J Trauma Resusc Emerg Med, 2011,19:64.
[17]Schochl H, Nienaber U, Hofer G, et al. Goaldirected coagulation management of major trauma patients using thromboelastometry (ROTEM)guided administration of fibrinogen concentrate and prothrombin complex concentrate. Crit Care, 2010,14(2):R55.
[18]Rourke C, Curry N, Khan S, et al. Fibrinogen levels during trauma hemorrhage, response to replacement therapy, and association with patient outcomes. J Thromb Haemost, 2012, 10(7):1342-1351.
[19]Holcomb JB, Minei KM, Scerbo ML, et al. Admission rapid thrombelastography can replace conventional coagulation tests in the emergency department: experience with 1974 consecutive trauma patients. Ann Surg, 2012,256(3):476-486.
[20]Afshari A, Wikkelso A, Brok J, et al. Thrombelastography (TEG) or thromboelastometry (ROTEM) to monitor haemotherapy versus usual care in patients with massive transfusion. Cochrane Database Syst Rev, 2011, (3):CD007871.
[21]Cotton BA, Dossett LA, Haut ER, et al. Multicenter validation of a simplified score to predict massive transfusion in trauma. J Trauma, 2010, 69 (Suppl 1):S33-S39.
[22]Callcut RA, Cotton BA, Muskat P, et al. Defining when to initiate massive transfusion: a validation study of individual massive transfusion triggers in PROMMTT patients. J Trauma Acute Care Surg, 2013, 74(1):59-65, 67-68.
[23]Nunez TC, Voskresensky IV, Dossett LA, et al. Early prediction of massive transfusion in trauma: simple as ABC (assessment of blood consumption)? J Trauma,2009, 66(2):346-352.
[24]Leemann H, Lustenberger T, Talving P, et al. The role of rotation thromboelastometry in early prediction of massive transfusion. J Trauma, 2010, 69(6):1403-1409.
[25]Schochl H, Cotton B, Inaba K, et al. FIBTEM provides early prediction of massive transfusion in trauma. Crit Care, 2011, 15(6):R265.
[26]Callcut RA, Johannigman JA, Kadon KS, et al. All massive transfusion criteria are not created equal: defining the predictive value of individual transfusion triggers to better determine who benefits from blood. J Trauma, 2011, 70(4):794-801.
[27]Cotton BA, Faz G, Hatch QM, et al. Rapid thrombelastography delivers realtime results that predict transfusion within 1 hour of admission. J Trauma, 2011, 71(2):407-417.
[28]Hincker A, Feit J, Sladen RN, et al. Rotational thromboelastometry predicts thromboembolic complications after major noncardiac surgery. Crit Care, 2014, 18(5):549.
[29]Harr JN, Moore EE, Chin TL, et al. Platelets are dominant contributors to hypercoagulability after injury. J Trauma Acute Care Surg, 2013, 74(3):756-765.

备注/Memo

备注/Memo:
﹡通讯作者，Email:13601076527@163.com
更新日期/Last Update: 2016-09-08