[1]金莹 郭红燕* 贺豪杰 韩劲松 朱馥丽 梁华茂 孔东丽.子宫内膜异位症患者的诊断延迟[J].中国微创外科杂志,2015,15(10):904-906.
 Jin Ying,Guo Hongyan,He Haojie,et al.Diagnostic Delay of Endometriosis[J].Chinese Journal of Minimally Invasive Surgery,2015,15(10):904-906.
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子宫内膜异位症患者的诊断延迟()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
15
期数:
2015年10期
页码:
904-906
栏目:
临床研究
出版日期:
2015-10-20

文章信息/Info

Title:
Diagnostic Delay of Endometriosis
作者:
金莹 郭红燕* 贺豪杰 韩劲松 朱馥丽 梁华茂 孔东丽
(北京大学第三医院妇产科,北京100191)
Author(s):
Jin Ying Guo Hongyan He Haojie et al.
Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China
关键词:
痛经子宫内膜异位症诊断延迟
Keywords:
DysmenorrheaEndometriosisDiagnostic delay
分类号:
R711.71
文献标志码:
A
摘要:
目的探讨子宫内膜异位症痛经患者诊断延迟的原因。方法制订《痛经及慢性盆腔痛调查表》,对2012年1月~2014年2月336例门诊就诊的痛经患者进行回顾性调查,分析子宫内膜异位症患者的诊断延迟情况。结果205例诊断为子宫内膜异位症,诊断延迟时间为10年(0~31年),初潮即痛经者,诊断延迟时间为15年(5~31年),明显大于初潮后痛经者(15 年 vs. 6年,Z=-7.547,P=0.000)。痛经逐渐加重的患者,诊断延迟时间小于无加重者(9年 vs.11年);合并伴随症状者,诊断延迟时间小于无伴随症状者(8年 vs. 10年);合并子宫腺肌症的患者,诊断延迟时间小于未合并者(8年 vs. 10年),但以上差异均无统计学意义(P>0.05)。结论子宫内膜异位症存在诊断延迟,初潮即痛经者,其诊断延迟的时间更长。痛经症状持续加重、合并伴随症状、合并子宫腺肌症,更有利于相对早期的诊断。
Abstract:
ObjectiveTo explore the causes of diagnostic delay of endometriosis.MethodsWe designed a dysmenorrhea and chronic pelvic pain questionnaire. Patients with dysmenorrhea who consulted in gynecological outpatient of the Peking University Third Hospital from January 2012 to February 2014 were asked to fill the questionnaire. Details of their dysmenorrhea were retrospectively analyzed, and the diagnostic delay of endometriosis were analyzed.ResultsA total of 205 patients were diagnosed as having endometriosis but had a median diagnostic delay of 10 years (0-31 years). Of the 205 cases, those suffering dysmenorrhea at menarche had a median of 15 years of diagnostic delay, longer than those who suffered dysmenorrhea after menarche (15 years vs. 6 years, Z=7.547, P=0.000). Patients with aggravating dysmenorrhea showed shorter diagnostic delay time than others (9 years vs. 11 year), and patients accompanying symptoms showed shorter diagnostic delay time than others (8 years vs. 10 years), and patients with adenomyosis also showed shorter diagnostic delay time than others (8 years vs. 10 years), but all of them had no statistically significant differences(P>0.05).ConclusionsThere is delay in the diagnosis of endometriosis. Patients with dysmenorrhea at menarche showed longer delay. Aggravating dysmenorrhea, accompanying symptoms and adenomyosis may relatively help early diagnosis.

参考文献/References:

[1]Latthe P, Latthe M, Say L, et al. WHO systematic review of prevalence of chronic pelvic pain: a neglected reproductive health morbidity. BMC Public Health, 2006, 6(6):177-183.
[2]王文莉,段华.子宫内膜异位症痛经机制的研究进展.中国微创外科杂志,2009, 9(12):1100-1102.
[3]Dunselman GA, Vermeulen N, Becker C, et al. ESHRE guideline: management of women with endometriosis. Hum Reprod,2014,29(3):400-412.
[4]The International Pelvic Pain Society. Pelvic pain assessment form. http: // www. pelvicpain. org/docs/resources/forms/History-and-Physical-Form-English. aspx,2008,4.
[5]冷金花, 郎景和, 李华军,等.子宫内膜异位症非手术诊断方法探讨. 现代妇产科进展, 2007, 16(11): 846-851.
[6]Brosens I, Gordts S, Benagiano G. Endometriosis in adolescents is a hidden, progressive and severe disease that deserves attention, not just compassion. Hum Reprod, 2013, 28(8): 2026-2031.
[7]Hadfield R, Mardon H, Barlow D, et al. Delay in the diagnosis of endometriosis: a survey of women from the USA and the UK. Hum Reprod, 1996, 11(4): 878-880.
[8]Brosens I, Puttemans P, Benagiano G. Endometriosis: a life cycle approach? Am J Obstet Gynecol, 2013, 209(4): 307-316.
[9]Bellelis P, Dias JA Jr, Podgaec S, et al. Epidemiological and clinical aspects of pelvic endometriosis–a case series. Rev Assoc Med Bras, 2010, 56(4): 467-471.
[10]Holland TK, Cutner A, Saridogan E, et al. Ultrasound mapping of pelvic endometriosis: does the location and number of lesions affect the diagnostic accuracy? A multicentre diagnostic accuracy study. BMC Womens Health, 2013, 13(10): 43-52.
[11]Hudelist G, Fritzer N, Thomas A, et al. Diagnostic delay for endometriosis in Austria and Germany: causes and possible consequences. Hum Reprod, 2012, 27(12): 3412-3416.
[12]Ballard K, Lowton K, Wright J. What’s the delay? A qualitative study of women’s experiences of reaching a diagnosis of endometriosis. Fertil Steril, 2006, 86(5): 1296-301.
[13]Nnoaham KE,Hummelshoj L,Webster P,et al.Impact of endometriosis on quality of life and work productivity:a multicenter study across ten countries.Fertil Steril,2011,96(2):366-373.
[14]Mihalyi A, Gevaert O, Kyama CM, et al. Non-invasive diagnosis of endometriosis based on a combined analysis of six plasma biomarkers. Hum Reprod, 2010,25(3): 654-664.

备注/Memo

备注/Memo:
*通讯作者,E-mail:bysyghy@163.com
更新日期/Last Update: 2016-02-03