[1]王海波 高丽彩 李秀娟 张爱群 马文巧 李苓妙 籍霞.腹腔镜与开腹手术治疗肥胖妇女早期子宫内膜癌的 对比研究[J].中国微创外科杂志,2015,15(6):515-530.
　Wang Haibo,Gao Licai,Li Xiujuan,et al.A Comparative Study of Laparoscopic and Open Operation for Early Endometrial Cancer in Obese Women[J].Chinese Journal of Minimally Invasive Surgery,2015,15(6):515-530.
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腹腔镜与开腹手术治疗肥胖妇女早期子宫内膜癌的 对比研究()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
15
期数:
2015年6期
页码:
515-530
栏目:
临床论著
出版日期:
2015-06-20

文章信息/Info

Title:
A Comparative Study of Laparoscopic and Open Operation for Early Endometrial Cancer in Obese Women
作者:
王海波 高丽彩 李秀娟 张爱群 马文巧 李苓妙 籍霞
解放军第260医院妇产科，石家庄050041
Author(s):
Wang Haibo;  Gao Licai;  Li Xiujuan;  et al.
No. 260 Hospital of People’s Liberation Army, Shijiazhuang 050041, China
关键词:
子宫内膜癌; 肥胖; 腹腔镜手术; 开腹手术
Keywords:
Endometrial cancer; Obesity; Laparoscopic operation; Open operation
分类号:
R737.33
文献标志码:
A
摘要:
目的探讨腹腔镜治疗肥胖妇女早期子宫内膜癌的可行性及临床效果。方法回顾分析2010年1月~2013年12月手术治疗的肥胖妇女早期子宫内膜癌患者的病历资料，均行子宫内膜癌根治术，其中腹腔镜组21例，开腹组30例。比较2组手术时间、术中出血量、淋巴结切除数量、术后排气时间、并发症及术后住院时间。结果与开腹组相比，腹腔镜组术中出血量少［（210.6±88.6）ml vs. （405.6±192.3）ml，t=-4.327，P=0.000］，术后肛门排气早［（2.2±1.2）d vs. （3.1±14）d，t=-2.390，P=0.021］，术后住院时间短［（13.3±4.4）d vs. （18.8±6.1）d，t=-3.534，P=0.001］。2组手术时间、清扫淋巴结总数、术后并发症差异无显著性。2组术后随访3～36个月，中位数29.6月，均未发现复发和死亡。结论腹腔镜手术治疗肥胖妇女子宫内膜癌的效果与开腹手术相同，且具有术中出血少、术后恢复快、并发症少等优点，适合在有一定的技术条件的医院开展。
Abstract:
ObjectiveTo investigate the feasibility and clinical efficacy of laparoscopic treatment for early endometrial cancer in obese women. MethodsClinical records of obese women with early endometrial cancer treated with radical resection from January 2010 to December 2013 were retrospectively analyzed. There were 21 cases of laparoscopic operations (laparoscopic group) and 30 cases of open operations (open group). The operation time, bleeding volume, number of lymph nodes removed, postoperative exhaust time, complications, and postoperative hospitalization time were compared between the two groups.ResultsThe amount of bleeding was significantly less in the laparoscopic group (210.6±88.6 ml) than in the open group (405.6±192.3 ml, t=-4.327, P=0.000). The anal exhaust time was significantly earlier in the laparoscopic group (2.2±1.2 d) than in the open group (3.1±14 d, t=-2.390, P=0.021). The hospital stay after laparoscopic surgery (13.3±4.4 d) was significantly shorter than that in the open group (18.8±6.1 d, t=-3.534, P=0.001). No statistical significance was found in the operation time between the laparoscopic group (220.8±66.4 min) and open group (199.6±60.4 min, t=1.184, P=0.242). The dissected lymph nodes showed no statistical significance between the laparoscopic group (18.2±6.6) and open group (16.8±6.2, t=0.764, P=0.449). There was no significantly statistical significance in postoperative complications between the two groups (χ2=0.386, P=0.534). The two groups were followed up for 3-36 months (median, 29.6 months) with no recurrence and death. ConclusionLaparoscopic operation for the treatment of endometrial cancer in obese women has the same effects as open operation, and has advantages of less bleeding, fast postoperative recovery, and fewer complications, being suitable to be developed in the hospital with technical feasibility.

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备注/Memo

备注/Memo:
*通讯作者，E-mail：whb6565@sina.com
更新日期/Last Update: 2015-06-20