[1]杨益民﹡ 张智 李萌 任志伟 马巍.记忆合金支架在椎体骨折中的实验研究[J].中国微创外科杂志,2014,14(8):751-754.
　Yang Yimin,Zhang Zhi,Li Meng,et al.Experimental Study of Memory Alloy Stent in the Treatment of Vertebral Compression Fracture[J].Chinese Journal of Minimally Invasive Surgery,2014,14(8):751-754.
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记忆合金支架在椎体骨折中的实验研究()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
14
期数:
2014年8期
页码:
751-754
栏目:
实验研究
出版日期:
2014-08-20

文章信息/Info

Title:
Experimental Study of Memory Alloy Stent in the Treatment of Vertebral Compression Fracture
作者:
杨益民﹡ 张智 李萌 任志伟 马巍
西安交通大学第一附属医院骨科，西安710061
Author(s):
Yang Yimin;  Zhang Zhi;  Li Meng;  et al.
Department of Orthopedics, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, China
关键词:
镍-钛记忆合金; 椎体压缩性骨折; 椎体后凸成形术
Keywords:
NiTi memory alloy; Vertebral compression fracture; Kyphoplasty
分类号:
R683.2
文献标志码:
A
摘要:
目的探讨自主研制的镍-钛记忆合金椎体支架（memory alloy vertebral stent）治疗椎体压缩性骨折的可行性。方法将成人尸体胸腰椎脊柱标本制成压缩性骨折模型，分成球囊扩张后植入镍-钛记忆合金椎体支架组(PKP+支架组)、直接植入镍-钛记忆合金椎体支架组(PVP+支架组)及球囊扩张后骨水泥填充组(PKP+PMMA组)。手术前后测量椎体高度，比较3组压缩椎体复位程度。 结果3组术后椎体高度均明显高于术前，PKP+支架组、PVP+支架组和PKP+PMMA组的椎体高度分别从术前的(1.59±0.08) cm、(1.68±0.08) cm和(1.66±0.11) cm复位至术后的(2.00±0.09) cm、(1.87±0.04) cm和(1.99±0.09) cm（t=-9.781、-7.952、-18.213，P=0.000、0.001、0.000）。各组手术前后椎体高度差比较，PKP+支架组［（0.39±0.09） cm］和PKP+PMMA组［（0.33±0.04） cm］明显大于PVP+支架组［（0.19±0.06） cm］（P=0000,0.003），而PKP+支架组与PKP+PMMA组差异无显著性（P=0.172）。结论镍-钛记忆合金椎体支架能有效地支撑、复位压缩的椎体终板，是对无神经症状的椎体骨折治疗方式的一种新的探索。
Abstract:
ObjectiveTo evaluate the feasibility of a selfdesigned NiTi memory alloy vertebral stent in the treatment of vertebral compression fractures. MethodsExperimental thoraciclumbar fracture models made from adult cadaver vertebral specimens were randomly assigned into 3 groups for testing: percutaneous balloon kyphoplasty with implanted NiTi memory alloy vertebral stent (PKP+stent group), percutaneous vertebroplasty with implanted NiTi memory alloy vertebral stent (PVP+stent group), and percutaneous balloon kyphoplasty with implanted polymethyl methacrylate cement (PKP+PMMA group). The vertebral height was measured before and after the three kinds of operations, respectively, to compare the restoration of compression fractures.ResultsIn all the three groups, the vertebral height of postoperation was significantly higher than the preoperation. The vertebral height of the PKP+stent group, PVP+stent group, and PKP+PMMA group was increased from (1.59±0.08) cm, (1.68±0.08) cm, and (1.66±0.11) cm before the operation to (2.00±0.09) cm, (1.87±0.04) cm, and (1.99±0.09) cm after the operation, respectively (t=-9.781, -7.952, and -18.213, P=0.000, 0.001, and 0.000). The subtract result before and after surgery on vertebral height was calculated. There were significant differences between the PKP+stent group and PVP+stent group ［(0.39±0.09) cm vs. (0.19±0.06) cm, P=0.000］, and between the PKP+PMMA group and PVP+stent group ［(0.33±004) cm vs. (0.19±0.06) cm, P=0.003］. However, there was no statistical difference between the PKP+stent group and PKP+PMMA group (P=0.172).ConclusionThe NiTi memory alloy vertebral stent can effectively support and restore the collapse of the vertebral endplate, and it is an effective treatment for vertebral compression fractures without nerval symptoms.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目：陕西省科学技术研究发展计划项目（2011K12-04-01）﹡通讯作者，Email：guke47@126.com
更新日期/Last Update: 2015-06-04