[1]张颖,段华,孔亮等.窄带成像宫腔镜在诊断子宫内膜癌及内膜非典型增生中的价值[J].中国微创外科杂志,2012,12(6):481-484.
　Zhang Ying,Duan Hua,Kong Liang,et al.Narrowband Imaging Hysteroscopy for the Diagnosis of Endometrial Cancer and Endometrial Atypical Hyperplasia[J].Chinese Journal of Minimally Invasive Surgery,2012,12(6):481-484.
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窄带成像宫腔镜在诊断子宫内膜癌及内膜非典型增生中的价值()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
12
期数:
2012年6期
页码:
481-484
栏目:
微创妇科
出版日期:
2012-06-15

文章信息/Info

Title:
Narrowband Imaging Hysteroscopy for the Diagnosis of Endometrial Cancer and Endometrial Atypical Hyperplasia
作者:
张颖; 段华; 孔亮等
首都医科大学附属北京妇产医院妇科微创诊治中心，北京100006
Author(s):
Zhang Ying;  Duan Hua;  Kong Liang;  et al.
Center of Minimally Invasive Surgery, Beijing Obstetrics and Gynecologic Hospital, Capital Medical University, Beijing 100006, China
关键词:
窄带成像; 宫腔镜; 子宫内膜癌; 子宫内膜非典型增生
Keywords:
Narrowband imaging; Hysteroscopy; Endometrial cancer; Atypical endometrial hyperplasia
分类号:
R737.330.4
文献标志码:
A
摘要:
目的探讨窄带成像（narrow band imaging，NBI）宫腔镜在子宫内膜癌及内膜非典型增生诊断中的应用价值。方法2009年6月~2011年6月，对189例异常子宫出血可疑子宫内膜病变患者行电子宫腔镜检查，对宫腔内膜依次使用白光和NBI模式进行分类和病灶性质的判断，以病理诊断作为金标准，比较两种观察模式对子宫内膜癌及内膜非典型增生诊断的作用。结果189例共取子宫内膜病理标本334份，其中病理阳性病灶（包括子宫内膜癌及子宫内膜非典型增生）127份，阴性病灶（正常子宫内膜及内膜良性病变）207份。依照子宫内膜癌及子宫内膜非典型增生的宫腔镜下诊断特征：病灶增厚高出周边内膜、异型血管和（或）组织坏死致病灶表面毛糙不规则，NBI及白光宫腔镜对子宫内膜癌及内膜非典型增生诊断的准确率为93.7％（313/334）及84.7％（283/334）(χ2=14.010，P=0.000)，敏感性为95.3％（121/127）及79.5％（101/127）(χ2=14.302，P=0.000)，NBI模式均显著高于白光；二者诊断的特异性为92.8％（192/207）及87.9％（182/207）(χ2=2.767，P=0.096)，差异无显著性。结论NBI弥补了普通光宫腔镜对病变形态学识别的不足，可明显提高对子宫内膜癌及内膜非典型增生诊断的敏感性和准确率，NBI指导下的对宫腔内病变的定位活检具有良好的临床应用前景。
Abstract:
ObjectiveTo evaluate the value of narrow band imaging (NBI) hysteroscopy in the diagnosis of endometrial cancer and atypical endometrial hyperplasia. MethodsFrom June 2009 to June 2011, a total of 189 patients with suspected endometrial lesions were examined with hysteroscopy equipped with the white light mode or NBI mode．With pathological diagnosis as a goldern standard, we evaluated the value of NBI hysteroscopy in detecting positive lesions inlcuding endometrial carcinoma and atypical endometrial hyperplasia (≥AEH). ResultsTotally 334 samples were obtained, including 127 positive lesions and 207 benign endometrial samples (

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备注/Memo

备注/Memo:
基金项目：卫生部行业项目专项基金（200802071）；国家临床重点专科建设项目（妇科）张颖段华通讯作者，Email：duanhua888@163.com
更新日期/Last Update: 2012-06-15