[1]吴开福,徐培坤,吴运,等.6例胶质瘤术后放射性脑病误诊为胶质瘤复发的临床分析[J].中国微创外科杂志,2012,12(2):136-139.
　Wu Kaifu,Xu Peikun,Wu Yun,et al.Six Cases of Postoperative Radiation Encephalopathy Misdiagnosed as Recurrent Glioma[J].Chinese Journal of Minimally Invasive Surgery,2012,12(2):136-139.
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6例胶质瘤术后放射性脑病误诊为胶质瘤复发的临床分析()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
12
期数:
2012年2期
页码:
136-139
栏目:
出版日期:
2012-02-25

文章信息/Info

Title:
Six Cases of Postoperative Radiation Encephalopathy Misdiagnosed as Recurrent Glioma
作者:
吴开福; 徐培坤; 吴运; 胡光东
安徽医科大学第一附属医院神经外科，合肥230022
Author(s):
Wu Kaifu;  Xu Peikun;  Wu Yun;  et al.
Department of Neurosurgery, First Affiliated Hospital, Anhui Medical College, Hefei 230022, China
关键词:
放射性脑病; 胶质瘤复发; 误诊
Keywords:
Radiation encephalopathy; Recurrent glioma; Misdiagnosis
分类号:
R730.550.6;R739.41
文献标志码:
A
摘要:
目的探讨胶质瘤术后放射性脑病与胶质瘤复发的鉴别。方法回顾分析我院2005年4月～2010年8月6例胶质瘤术后经放射治疗误诊为胶质瘤复发的临床资料。结果5例病变全切，1例大部切除（切除90%）。6例病理结果为放射性脑病。1例术后右侧肢体肌力较术前转差（术前Ⅳ级，术后Ⅰ~Ⅱ级）。术后9～14 d出院。6例随访6～24个月，平均9.5月，患者恢复良好，1例术后8个月因胶质瘤复发再次入院。结论胶质瘤术后放射性脑病与胶质瘤复发难以区别，临床上容易误诊，应综合患者病史、复发时间、临床症状、影像学表现等多因素特征，提高临床鉴别诊断水平，降低误诊率的发生。
Abstract:
ObjectiveTo investigate the differentiation diagnosis between recurrent glioma and postoperative radiation encephalopathy. MethodsWe reviewed retrospectively the clinical data of 6 cases of glioma which were misdiagnosed as recurrent tumor after surgical treatment and radiotherapy in our hospital between April 2005 and August 2010. ResultsIn the 6 cases, total excision was performed on 5 cases, and partial removal (90%)in the other one. Pathological examination showed radiation encephalopathy in all the 6 cases. One of the patients showed lower strength of the left limb (decreased from grade Ⅳ preoperation to grade Ⅰ-Ⅱ postoperation). The patients were discharged from the hospital in 9 to 14 days, and 6 of them were followed up for a mean of 9.5 months (6-24 months). All the patients recovered well, except for one, who was admitted to hospital again in 8 months because of recurrent glioma. ConclusionsIt is difficult to differentiate radiation encephalopathy from recurrent glioma. Medical history, recurrent time, symptoms, imaging results may contribute to diagnosis.

参考文献/References:

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备注/Memo

备注/Memo:
徐培坤 通讯作者，Email:xpk5909@163.com
更新日期/Last Update: 2013-04-11