[1]覃道芬,陈峰,陈杰,等.鼻内镜下三层移植物鼻中隔穿孔修补术[J].中国微创外科杂志,2009,09(7):644-650.
　Qin Daofen,Chen Feng,Chen Jie,et al.Repair of Nasal Septal Perforation with Threelayer Graft under Nasal Endoscope[J].Chinese Journal of Minimally Invasive Surgery,2009,09(7):644-650.
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鼻内镜下三层移植物鼻中隔穿孔修补术()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
09
期数:
2009年7期
页码:
644-650
栏目:
出版日期:
2009-08-25

文章信息/Info

Title:
Repair of Nasal Septal Perforation with Threelayer Graft under Nasal Endoscope
作者:
覃道芬; 陈峰; 陈杰; 俞晨杰; 高下
南京大学医学院附属南京鼓楼医院耳鼻咽喉科，南京210008
Author(s):
Qin Daofen;  Chen Feng;  Chen Jie;  et al.
Department of Otorhinolaryngology, Drum Tower Hospital, Nanjing Uiniversity Medical School, Nanjing 210008, China
关键词:
鼻内镜; 鼻中隔穿孔; 修补术; 移植物
Keywords:
Nasal　endoscope; Perferation of nasal septum; Neoplasty; Graft
分类号:
R765.3+4
文献标志码:
A
摘要:
目的探讨鼻内镜下应用三层移植物修补鼻中隔穿孔的疗效。方法2002年6月～2007年6月对15例鼻中隔穿孔应用阔筋膜包裹自体或异体的鼻中隔软骨板或筛骨垂直板形成的三层移植物修补，穿孔时间6月～5年，平均1.8年；穿孔直径0.8～1.6 cm，平均1.2 cm。在鼻内镜下刮除鼻中隔穿孔边缘黏膜上皮,造成新鲜创缘,用鼻中隔黏膜下矫正术的方法分离鼻中隔穿孔周围的黏软骨膜及骨膜，取合适大小的大腿阔筋膜，包绕自体或异体的鼻中隔软骨板或筛骨垂直板形成的三层移植物封闭穿孔,两侧鼻腔填塞膨胀海绵,注射碱性成纤维细胞生长因子让其膨胀，使穿孔缘黏膜与移植物完全贴合。结果术后6～10周鼻腔黏膜上皮完全覆盖移植物，鼻中隔穿孔愈合。15例随访6～12个月，平均8.2月，未发生再穿孔。结论鼻内镜下应用三层移植物修补鼻中隔穿孔是治疗中等程度以上鼻中隔穿孔的有效方法。
Abstract:
ObjectiveTo explore the efficacy of nasal septal perferation with three layers of grafts under nasal endoscope.MethodsFrom June 2002 to June 2007, 15 cases of nasal septal perforation were repaired by three laryers of grafts using the perpendicular plate of the ethmoid bone or quadrangular cartilage covered by fascia lata of the thigh. The course of the disease ranged from 6 months to 5 years (mean, 1.8 years) and the diameter of the perforation ranged from 0.8 to 1.6 cm (mean, 1.2 cm). A 1-2 mm new surface was made along the margin of the perforation, and then the nasal septum was separated by means of submucos correction. Afterwards, a perpendicular plate of the ethmoid bone or quadrangular cartilage covered by fascia lata of the thigh was used to form a threelayer graft for seal of the perforation. Then, the nasal cavities were filled with expansive sponge, which was expanded by injecting lyophilized recombinant bovine basic fibroblast growth factor for external use.ResultsThe surface of the graft was completely covered by nasal mucosa in 6 to 12 weeks after the surgery.Afterwords,the patients were followed up for 6 to 12 months (mean, 8.2 months), during which no recurrence occurred.ConclusionsIt is effective to repair nasal septal perforation with threelayer graft under nasal endoscope.

参考文献/References:

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[3]黄谦,周兵,韩德民,等. 鼻内镜下鼻中隔穿孔修补术. 中华耳鼻咽喉头颈外科杂志, 2005, 40 (8):579-581.
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更新日期/Last Update: 2013-09-17