[1]张雪垠,葛春晓*.531例不孕与不育宫腔镜诊断的宫腔病因分析[J].中国微创外科杂志,2008,08(10):917-919.
　Zhang Xueyin,Ge Chunxiao..Etiological Diagnosis by Hysteroscopy in 531 Patients with Infertility Complicated with Intrauterine Disorders[J].Chinese Journal of Minimally Invasive Surgery,2008,08(10):917-919.
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531例不孕与不育宫腔镜诊断的宫腔病因分析()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
08
期数:
2008年10期
页码:
917-919
栏目:
出版日期:
2008-11-04

文章信息/Info

Title:
Etiological Diagnosis by Hysteroscopy in 531 Patients with Infertility Complicated with Intrauterine Disorders
作者:
张雪垠; 葛春晓*
南京医科大学鼓楼临床医学院妇产科，南京210008
Author(s):
Zhang Xueyin;  Ge Chunxiao.
Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Nanjing Medical University, Nanjing 210008, China
关键词:
宫腔镜检查; 病因学; 不育; 女（雌）性
Keywords:
Hysteroscopy;  Etiology; Infertility; Female
分类号:
R711.6；R713.04
文献标志码:
A
摘要:
目的探讨引起女性不孕与不育的宫腔病因。方法1993年3月～2008年3月，对不孕与不育患者做宫腔镜检查，对资料完整的2077例中诊断有宫腔疾病的531例作回顾性总结与分析。其中原发不孕症（原发组）172例（324%），继发不孕症（继发组）315例（593%），不育(不育组)44例（83%）。结果宫腔主要病因：宫腔粘连231例（435%），子宫畸形152例（286%），子宫内膜息肉88例（166%）。3组比较：原发组以子宫内膜息肉为主（384%，66/172），明显高于继发组(60%，19/315)和不育组（68%，3/44） (χ2=807630，P=0000； χ2=160463，P=0000)；继发组以宫腔粘连为主（606%，191/315），明显高于不育组（250%，11/44）和原发组(169%，29/172)(χ2=199232，P=0000； χ2=860747，P=0000)；不育组以子宫畸形为主（659%，29/44），明显高于继发组（251%，79/315）和原发组(256%，44/172)(χ2=305994，P=0000； χ2=254673，P=0000)。结论不孕与不育的主要宫腔病因：原发不孕是子宫内膜息肉；继发不孕是宫腔粘连；不育是子宫畸形。
Abstract:
ObjectiveTo explore the intrauterine disorders that leads to infertility and sterility in women.MethodsFrom March 1993 to March 2008, a total of 2077 patients with infertility received hysteroscopic examination at Nanjing Drum Tower Hospital. Among the patients, 531 were diagnosed with intrauterine abnormalities including primary infertility in 172 (324%) cases, secondary infertility in 315 cases (593%), and sterility in 44 (83%). The clinical data of these patients were analyzed retrospectively.ResultsThe most common cause of infertility and sterility in the patients was intrauterine adhesion (231 cases, 435%), followed by uterine deformities (152, 286%) and endometrial polyps (88, 166%). In the primary infertility group, the most common reason was endometrial polyps, which was detected in 38.4% of the cases (66/172). The rate was significantly higher than that in the secondary infertility group (60%, 19/315) and sterility group (68%, 3/44) (χ2=807630，P=0000； χ2=160463，P=0000).While in the secondary infertility group, intrauterine adhesion was detected in most of the patients (606%, 191/315), that was significantly more than that in the sterility and primary groups (250%, 11/44, χ2=199232, P=0000 and 169%, 29/172, χ2=860747, P=0000, respectively). For the patients with sterility, the disease was caused by uterine deformities mostly (659%, 29/44), which is significantly different from the other two groups (secondary group: 251%, 79/315, χ2=305994, P=0000; primary group: 256%, 44/172, χ2=254673, P=0000).ConclusionThe major causes of primary infertility, secondary infertility, and sterility are endometrial polyp, intrauterine adhesion, and uterine deformities respectively.

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备注/Memo

备注/Memo:
*通讯作者（南京大学医学院附属鼓楼医院妇产科，南京210008）
更新日期/Last Update: 2013-10-23