[1]钱晓云,俞晨杰,沈晓辉,等.支撑喉镜下吸引旋切结合射频治疗喉癌前病变的疗效评价[J].中国微创外科杂志,2008,08(2):104-106.
　Qian Xiaoyun,Yu Chenjie*,Shen Xiaohui*,et al.Effectiveness of Microresection Combined with Radiofrequency Ablation under Laryngoscope and Rigid Telescope for Laryngeal Precancerosis[J].Chinese Journal of Minimally Invasive Surgery,2008,08(2):104-106.
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支撑喉镜下吸引旋切结合射频治疗喉癌前病变的疗效评价()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
08
期数:
2008年2期
页码:
104-106
栏目:
出版日期:
2008-10-24

文章信息/Info

Title:
Effectiveness of Microresection Combined with Radiofrequency Ablation under Laryngoscope and Rigid Telescope for Laryngeal Precancerosis
作者:
钱晓云; 俞晨杰; 沈晓辉; 丁小琼; 杨烨; 顾亚军; 高下**
南京大学医学院附属鼓楼医院耳鼻咽喉－头颈外科，南京210008
Author(s):
Qian Xiaoyun;  Yu Chenjie*;  Shen Xiaohui*;  et al.
*Department of Otorhinolaryngology, DrumTower Hospital, Nanjing University Medical School, Nanjing 210008, China
关键词:
支撑喉镜; 吸引旋切技术; 癌前病变
Keywords:
Laryngoscopy; Microresection; Precancerosis
分类号:
R739.65
文献标志码:
A
摘要:
目的探讨支撑喉镜下吸引旋切结合射频治疗喉部癌前病变的疗效。方法对51例临床诊断并经病理证实为癌前病变者采用支撑喉镜下吸引旋切结合射频治疗，随访>6个月。 结果随访6个月~4.5年，平均26个月，复发7例（声带白斑3例、不典型增生2例、喉乳头状瘤2例），癌变4例（声带白斑1例、不典型增生2例、喉乳头状瘤1例），2例双侧声带白斑者术后发生喉蹼。术后1个月嗓音分析基频微扰(Jitter)、振幅微扰(Shimmer)和声门噪声能量(NNE)较术前降低（P<0.01）。结论支撑喉镜下吸引旋切结合射频治疗喉部癌前病变是一种易于推广的微创喉部技术，能在彻底清除病变的同时,最大程度保留喉功能。
Abstract:
ObjectiveTo investigate the effectiveness of microresection combined with radiofrequency ablation under laryngoscope and rigid telescope for laryngeal precancerosis.MethodsFiftyone patients with laryngeal precancerosis, which was diagnosed pathologically, were treated with microresection combined with radiofrequency ablation under laryngoscope and rigid telescope. The patients were followed up for over 6 months.ResultsDuring a mean of 26month followup (6 months to 4.5 years), 7 of the patients had recurrence (vocal cord leukoplakia in 3, atypical hyperplasia in 2, and laryngeal papilloma in 2); 4 had carcinomatous change (vocal cord leukoplakia in 1, atypical hyperplasia in 2, and laryngeal papilloma in 1);and 2 patients developed laryngeal web after surgical treatment for bilateral vocal cord leukoplakia. One month after the operation, the Jitter, Shimmer, and NNE were decreased significantly (P<0.01).ConclusionsMicroresection combined with radiofrequency ablation under laryngoscope and rigid telescope for laryngeal precancerosis is effective, minimally invasive, and easy learning. By using the method, the laryngeal lesion could be resected, while maintaining the function of the larynx as much as possible.

参考文献/References:

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备注/Memo

备注/Memo:
江苏省科技厅社会发展项目（编号BS2005009）**通讯作者①南京大学医学院2004级在职研究生
更新日期/Last Update: 2013-10-22