[1]翟晓梅,聂兴举,秦泽莲**,等.胸腺素β4基因片断mRNA在人瘢痕及皮肤组织中的表达定位[J].中国微创外科杂志,2007,07(12):1217-1220.
 Zhai Xiaomei,Nie Xingju,Qin Zelian,et al.Location of Thymosin β4 mRNA Expression in Scars and Skins[J].Chinese Journal of Minimally Invasive Surgery,2007,07(12):1217-1220.
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胸腺素β4基因片断mRNA在人瘢痕及皮肤组织中的表达定位()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
07
期数:
2007年12期
页码:
1217-1220
栏目:
基础研究
出版日期:
2007-12-20

文章信息/Info

Title:
Location of Thymosin β4 mRNA Expression in Scars and Skins
作者:
翟晓梅聂兴举秦泽莲**赵霞李健宁
北京大学第三医院成形外科,北京100083
Author(s):
Zhai Xiaomei Nie Xingju Qin Zelian et al.
Department of Plastic Surgery, Peking University Third Hospital, Beijing 100083, China
关键词:
胸腺素β4瘢痕疙瘩增生性瘢痕皮肤原位杂交
Keywords:
Thymosin β4KeloidsHypertrophic scarSkinIn situ hybridization
分类号:
R34
文献标志码:
A
摘要:
目的研究胸腺素β4(thymosin β4,Tβ4)基因片断mRNA在人包皮及其他部位正常皮肤、瘢痕疙瘩、增生性瘢痕组织中的表达,探讨其表达与病理性瘢痕发生的相关性。方法采用地高辛标记Tβ4基因片断 [BM005698(EST)基因]探针,利用组织切片的原位杂交技术显示Tβ4 mRNA的表达,分别进行定性和体视学半定量分析4组标本的Tβ4表达情况。结果Tβ4基因片断的mRNA在大部分包皮及其他部位正常皮肤、增生性瘢痕、瘢痕疙瘩中表达,瘢痕疙瘩的成纤维细胞表达Tβ4的阳性标本比率(2/10)仅为包皮(8/1
Abstract:
ObjectiveTo investigate the expression of thymosin β4 in the foreskin, normal skin (except the foreskin), hypertrophic scar, and keloid, and its relationship to pathological scars.MethodsIn situ hybridization was applied to detect the expression of thymo

参考文献/References:

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备注/Memo

备注/Memo:
国家自然科学基金资助课题(30170971),**通讯作者
更新日期/Last Update: 2013-12-10