[1]杨晓平①,卜建国①,蔡秀军.腹腔镜胆囊切除术的手术时间对机体应激反应的影响[J].中国微创外科杂志,2007,07(9):912-914.
　Yang Xiaoping,Bu Jianguo,Cai Xiujun*..Effects of Different Operation Time of Laparoscopic Cholecystectomy on Systemic Stress Response[J].Chinese Journal of Minimally Invasive Surgery,2007,07(9):912-914.
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腹腔镜胆囊切除术的手术时间对机体应激反应的影响()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
07
期数:
2007年9期
页码:
912-914
栏目:
实验研究
出版日期:
2007-09-20

文章信息/Info

Title:
Effects of Different Operation Time of Laparoscopic Cholecystectomy on Systemic Stress Response
作者:
杨晓平①; 卜建国①; 蔡秀军
浙江大学医学院附属邵逸夫医院普外科,杭州310016
Author(s):
Yang Xiaoping;  Bu Jianguo;  Cai Xiujun*.
*Department of General Surgery, Sir Run Run Shaw Hospital, Medical College of Zhejiang University, Hangzhou 310016, China
关键词:
胆囊切除术; 腹腔镜; 手术时间; 机体应激反应
Keywords:
Cholecystectomy; Laparoscopy; Operation time; Systemic stress response
分类号:
R657.4
文献标志码:
A
摘要:
目的研究腹腔镜胆囊切除术时间长短对机体应激反应的影响。方法将40例需行腹腔镜胆囊切除术患者按手术时间长短分为Ａ组(<1 ｈ)和Ｂ组(≥1 ｈ)，每组20例。围手术期测C反应蛋白（CRP）、白介素6（IL6）、促肾上腺皮质激素（ACTH）及皮质醇浓度,并观察术后体温、疼痛情况。结果术后第1天最高体温A组低于B组［（37.1±0.4）℃ vs （37.5±0.7）℃，t=-2.219，P=0.033］。术后疼痛评分A组低于B组［中位数2（2~4） vs 4（3~6），χ2=3.806，P=0.021］；血IL6、CRP、ACTH和皮质醇两组手术后均明显升高(P<0.05)，且B组升高比A组明显。 结论腹腔镜胆囊切除术手术时间延长增强了机体术后应激反应。
Abstract:
ObjectiveTo study the effects of different operation time of laparoscopic cholecystectomy(LC) on systemic stress response.MethodsA total of 40 patients conducted by LC were divided into the Group A (<1 h) and Group B (≥1 h) according to the length of operation time, with 20 cases in each group. C reactive protein (CRP), IL6, ACTH and cortisol were measured perioperatively, and postoperative pain and body temperature were observed.ResultsAs compared with the Group B, the peak of body temperature the following day after operation was significantly lower in the Group A［(37.1±0.4)℃ vs (37.5±0.7)℃, t=-2.219,P=0.033］. The score of postoperative pain in the Group A was also strikingly lower than that in the Group B［median 2(2-4) vs 4(3-6), χ2=3.806,P=0.021］. Plasma levels of IL6、CRP、ACTH and cortisol significantly increased after operation in both groups (P<0.05), while a more evident increase was found in the Group B.ConclusionsThe systemic stress response is enhanced by prolonged operation time of LC.

参考文献/References:

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备注/Memo

备注/Memo:
①（浙江省台州市中心医院普外科，台州318000）
更新日期/Last Update: 2013-12-09