[1]黄毅,王俊杰,冉维强,等.前列腺癌125I放射粒子植入术后直肠并发症及防治[J].中国微创外科杂志,2007,07(2):125-126.
　Huang Yi*,Wang Junjie,Ran Weiqiang,et al.Prevention and treatment of rectal complications after 125I brachytherapy for prostate cancer[J].Chinese Journal of Minimally Invasive Surgery,2007,07(2):125-126.
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前列腺癌125I放射粒子植入术后直肠并发症及防治()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
07
期数:
2007年2期
页码:
125-126
栏目:
出版日期:
2007-02-20

文章信息/Info

Title:
Prevention and treatment of rectal complications after 125I brachytherapy for prostate cancer
作者:
黄毅; 王俊杰; 冉维强; 洪锴; 马璐林
北京大学第三医院泌尿外科，北京100083
Author(s):
Huang Yi*;  Wang Junjie;  Ran Weiqiang; et al.
*Department of Urology, Peking University Third Hospital, Beijing 100083, China
关键词:
前列腺癌; 125I粒子植入; 尿道直肠瘘
Keywords:
Prostate cancer; 125I brachytherapy; Urethrorectal fistula
分类号:
R737.25;R730.6;R817.8
文献标志码:
A
摘要:
目的探讨前列腺癌125I粒子植入术后直肠并发症及防治。方法2001年11月～2006年6月，在直肠超声引导下，经会阴前列腺125I放射粒子植入联合雄激素全阻断治疗中晚期前列腺癌90例，术后每1～3个月随访，观察直肠并发症及治疗。结果89例随访1～55个月，平均22个月。直肠并发症 Ⅰ、Ⅱ、Ⅲ、Ⅳ级发生率分别为11.2%(10/89)、6.7%(6/89)、0%及2.2%(2/89)。Ⅰ、Ⅱ级16例观察及对症治疗，半年后症状逐渐减轻。Ⅳ级2例，1例因直肠炎在外院行多次检查和治疗，1例合并重度糖尿病，采用结肠腹壁造口，结合膀胱穿刺造瘘治疗，病情好转。结论125I放射粒子植入术后发生放射性直肠炎，一般采用观察及对症治疗，病情有自限性，不要盲目过度检查及治疗，对合并糖尿病者应积极治疗，以减少尿道直肠瘘的发生。
Abstract:
ObjectiveTo evaluate the prevention and treatment of rectal complications following 125I brachytherapy for prostate cancer.MethodsA total of 90 patients with locally advanced prostate cancer was treated by transrectal ultrasound guided prostate 125I brach

参考文献/References:

[1]Grimm PD, Blasko JC, Sylvester JE, et al.10year biochemical (prostatespecific antigen) control of prostate cancer with (125)I brachytherapy. Int J Radiat Oncol Biol Phys， 2001,51(6):31-40.
[2]Hu K, Wallner K. Clinical course of rectal bleeding following I125 prostate brachytherapy. Int J Radiat Oncol Biol Phys，1998,41(2):263-265.
[3]王俊杰.放射性粒子种植治疗前列腺癌.中国微创外科杂志，2002，2（2）：82-84.
[4]Kang SK, Chou RH, Dodge RK, et al. Gastrointestinal toxicity of transperineal interstitial prostate brachytherapy. Int J Radiat Oncol Biol Phys，2002,53(1):99-103.
[5]Sherertz T, Wallner K, Merrick G,et al. Factors predictive of rectal bleeding after 103Pd and supplemental beam radiation for prostate cancer. Brachytherapy,2004,3:130-135.
[6]Stone NN, Stock RG. Complications following permanent prostate brachytherapy. Eur Urol,2002,41(4):427-433.
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[8]Lane BR, Stein DE, Remzi FH, et al. Management of radiotherapy induced rectourethral fistula.J Urol,2006,175:1382-1388.

备注/Memo

备注/Memo:
①放疗科②超声科
更新日期/Last Update: 2013-11-15