[1]罗萍香,李穗湘.米非司酮联合腹腔镜手术保守性治疗输卵管妊娠的价值[J].中国微创外科杂志,2006,06(2):111-112.
 Luo Pingxiang,Li Suixiang..Conservative treatm ent of tubal pregnancy using mifepristone and laparoscopy[J].Chinese Journal of Minimally Invasive Surgery,2006,06(2):111-112.
点击复制

米非司酮联合腹腔镜手术保守性治疗输卵管妊娠的价值()
分享到:

《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
06
期数:
2006年2期
页码:
111-112
栏目:
出版日期:
2006-02-20

文章信息/Info

Title:
Conservative treatm ent of tubal pregnancy using mifepristone and laparoscopy 
作者:
罗萍香李穗湘
广东韶关市第一人民医院妇科,韶关,512000
Author(s):
Luo Pingxiang Li Suixiang.
Department of Gynecology, Shaoguan First People’s Hospital, Shaoguan 512000, China
关键词:
米非司酮腹腔镜输卵管妊娠
Keywords:
Mifepristone Laparoscope Tubal pregnancy
分类号:
R713.8
文献标志码:
A
摘要:
目的探讨米非司酮联合腹腔镜手术治疗输卵管妊娠的价值.方法选择符合条件的输卵管妊娠64例,随意分为2组,各32例.研究组:术前24 h给予1次顿服米非司酮150 mg;对照组:术前不服药.结果研究组:术中出血量为232.0±170.6 ml,手术时间35.2±5.8 min;对照组:术中出血量为391.9±239.2 ml,手术时间40.8±6.1 min,差异有显著性(t分别为-3.079,-3.764,P值均<0.01).研究组全部保守手术成功,对照组输卵管切除3例,切除率为9.4%;研究组无持续性异位妊娠,对照组2例持续性异位妊娠,发生率为6.3%.结论输卵管妊娠行腹腔镜手术前服用米非司酮,可使腹腔镜手术出血少,保守性手术成功率高,术后持续性异位妊娠发生率低.值得在临床上推广使用.
Abstract:
Objective To evaluate the effectiveness oforal administration ofmifepristone combinedwith laparoscopy for tubal pregnancy. M ethods A total of64 patientswere freely divided into two groups: the StudyGroup (n=32) and the ControlGroup (n=32). The StudyGroupwas given 150 mgmifepristone 24 h before laparoscopy and the ControlGroupwas notgivenmifepristone. Results The intraoperative hemorrhage volume and the operation timewere 232. 0±170. 6 ml and 35. 2±5. 8 min in the StudyGroup and 391. 9±239. 2 ml and 40. 8±6. 1 min in the ControlGroup, respectively, with significant differences between the two groups (P<0·01). The conservative operationwas successfully completed in allpatients in the StudyGroupwhile salpingectomywas required in 3 patients in the ControlGroup (9. 4% ). Persistent ectopic pregnancy occurred in no patients in the StudyGroup and in 2 patients in the Control Group (6. 3% ). Conclusions Oral administration of mifepristone perior prior to conservative laparoscopy can minimize intraoperative hemorrhage, increase the success rate of conservative operation, and decrease the incidence of postoperative persistent ectopic pregnancy.

参考文献/References:

[1]刘珠凤,孙正怡,杨佳欣,等.持续性异位妊娠的诊断及治疗.中华医学杂志,2001,81(21):1261-1263.
[2]练晓勤,陈强.葡萄糖溶液冲洗剥离面止血在腹腔镜保守治疗输卵管妊娠的价值.中国微创外科杂志,2004,4(4):116-117.
[3]乐杰,主编.妇产科学.第6版.北京:人民卫生出版社,2003.397-398.
[4]高郁森,李志凌.输卵管妊娠腹腔镜手术后持续性异位妊娠的发生.中国内镜杂志,2004,5(5):36-38.
[5]Ben Arie A,Gotdchmit R,Dgani R,et al.Trophoblastic peritoneal implants after laparoscopic treatment of ectopic pregnancy.Ear J Obstet Gynecol Reprod Biol,2001,96(1):36-38.
[6]刘正蓉,杨淑华,高华,腹腔镜保留输卵管手术治疗输卵管妊娠56例报告.中国微创外科杂志,2004,4(6):500-501.

更新日期/Last Update: 2014-01-27