[1]崔伟珍,甄作均①,陈焕伟①,等.超声检查技术对于射频消融治疗肝癌的疗效评价[J].中国微创外科杂志,2005,05(2):102-104.
　Cui Weizhen*,Zhen Zuojun,Chen Huanwei,et al.Ultrasound evaluation of efficacy of radiofrequency thermal ablation in the treatment of hepatic carcinoma[J].Chinese Journal of Minimally Invasive Surgery,2005,05(2):102-104.
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超声检查技术对于射频消融治疗肝癌的疗效评价()
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《中国微创外科杂志》[ISSN:1009-6604/CN:11-4526/R]

卷:
05
期数:
2005年2期
页码:
102-104
栏目:
出版日期:
2005-02-28

文章信息/Info

Title:
Ultrasound evaluation of efficacy of radiofrequency thermal ablation in the treatment of hepatic carcinoma
作者:
崔伟珍; 甄作均①; 陈焕伟①; 王军华①; 黄伟俊
广东省佛山市第一人民医院腹部超声科,佛山,528000
Author(s):
Cui Weizhen*; Zhen Zuojun;  Chen Huanwei;  et al.
Department of Ultrasonography, Foshan First People’sHospital, Foshan 528000, China
关键词:
超声;  射频消融;  肝癌;  疗效评价
Keywords:
Ultrasound; 　Radiofrequency ablation; 　Hepatic carcinoma; 　Efficacy evaluation
分类号:
R735.704.51
文献标志码:
A
摘要:
目的探讨超声检查技术评价射频消融治疗肝癌疗效的意义. 方法超声引导下对49例66个肝癌病灶行多弹头射频消融治疗,超声检查病灶术前术后的大小及回声、血流信号及频谱等作为评价该术疗效的超声监测指标,以CT作对照检查,观察术前术后AFP或CEA下降幅度. 结果术后1个月超声检查,其中42例59个病灶(89.4%)瘤体内可见"爪状"不均质高回声改变覆盖整个瘤体,其内未检出血流信号,此后瘤体逐渐缩小或不增大,回声趋于等回声改变,结合AFP或CEA值明显下降或降至正常水平,提示术后疗效良好;另7例7个病灶(10.6%)瘤体内部分回声未改变,其内检出动脉血流信号,AFP或CEA值下降不明显,提示第一次射频消融治疗不彻底,需要进行第二次追加治疗.术后1个月复查CT显示9例9个病灶有强化,其中7例7个病灶与超声检查提示一致.与CT检查对照分析,超声检查对病灶内血流检出的敏感性为55.6%(5/9),特异性为96.5%(55/57),准确性为90.9%(60/66). 结论超声检查技术亦可作为评价射频消融治疗肝癌疗效的一种有效手段.
Abstract:
Objective　To discuss the value of ultrasonography in the evaluation of efficacy of radiofrequency (RF) thermal ablation for hepatic carcinoma.　M ethods　A total of49 patientswith 66 lesions ofhepatic carcinoma underwentultrasound-guided multipolar radiofrequency ablation. Ultrasound examinations were carried out on tumor sizes, echo signals, vascular flows and frequency spectrums before and after the treatment. Moreover, AFP orCEA levels before and after the procedurewere observed. And the CT scanning results were regarded as the contro.l　Results　Ultrasound examinations 1 month after the ablation found that “claw-like”heterogeneous hyperechoic changes covered thewhole tumorswithoutvascular flows inside in 42 patientswith 59 lesions (89·4% ). Afterwards, the tumors gradually reduced or remained unchanged in size, with a homogeneous echo texture. The serum levels ofAFP orCEA markedly reduced ordropped down to norma.l Allof thesewere suggestive of an excellent curative effect. In the remaining 7 patients with 7 lesions (10·6% ), intratumoral echo pattern kept unchanged, with arterial flow signals inside and unremarkable decrease ofAFP or CEA levels, all ofwhich were suggestive of an unsatisfactory outcome of the first radiofrequency treatment and a requirement of an additional radiofrequency treatment. CT examinations 1 month after the ablation revealed an enhancementof lesions in 9 patientswith 9 lesions, amongwhich the CT resultswere in agreementwith the ultrasound outcomes in 7 patientswith 7 lesions. Compared with the enhanced CT scans, ultrasonography in the detection of intratumoral vascular flows had a sensitivity of55·6% (5/9), a specificity of96·5% (55/57) and an accuracy of90·9% (60/66).　Conclusions　Ultrasonography is an effective alternative for the evaluation of efficacy of radiofrequency thermal ablation in the treatment ofhepatic carcinoma.

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备注/Memo

备注/Memo:
基金项目：本课题为广东省医学科研基金项目(A2002696)，①肝胆外科
更新日期/Last Update: 2014-03-11