三维适形放射治疗肝转移瘤——附10例报告-《中国微创外科杂志》

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Title:: The therapeutic effect of 3D-conformal radiotherapy on metastatic hepatic cancer

Author(s):: Zhao Weisheng; Jiang Wei; Cong Zheng; et al.; Tianjin huanhuHospital, Tianjin300060, China

摘要:: 目的探讨三维适形放射治疗对肝转移瘤的治疗效果. 方法 1997/09～2000/04采用立体定向适形放射治疗10例肝转移瘤(1～5个转移灶).肿瘤的临床靶体积(CTV)为0.6cm3～232cm3(平均41.9cm3),计划靶体积(PTV)周边剂量为每次照射3.96～7.0Gy(平均5.26Gy),PTV中心剂量为每次照射6.3～10.88Gy(平均7.89Gy),每天一次,每周5次,共5～8次. 结果病人一般状况的计分标准(KPS):术前20～90分(54±25.9分),术后30～100分(74±23.

Abstract:: Ojective　To evaluate the therapeutic effect of conformal radiotherapy on metastatic hepatic can- cer.　Methods　10 cases ofmetastatic hepatic cancer (1 to 5 metastatic focus respectively) were treatedwith stereo- tactic radiotherapy from Septermber 1997 to April 2000. The clinical target volume(CTV) of tumor ranged from 0. 6cm3to 232cm3(the mean 41.9cm3), peripheral irradiation doses of planning target volume (PTV) ranged from 3. 96Gy to 7.00Gy(the mean 5.26Gy)each time, cential irradiation doses of PTVwere 6.3Gy~10.88Gy (the mean 7. 89Gy) each time, once a day for5~8 times totally.　Results　No patient died duringtherapy. KPS of patients nor- mal condition were 20~90(54±25.90) before treatment and 30~100 (74±23.90) after treatment. Effect of entity tumor were as follows completely relaxed (CR) in two cases, partly relaxed (PR) in four cases, no change (NC) in three cases, progressed (PD) in one case. During follow-up period tasting 2 to 28 months 90% of the tumors were controlled (no progressive disease). 60% fo the tumors decreased in size or disappeared.　Conclusions　Stereotac- tic radiotherapy has better therapeutic effects on cases of metastatic hepatic cancer.